S
Saulo R. Tintino
Researcher at Laboratory of Molecular Biology
Publications - 135
Citations - 2498
Saulo R. Tintino is an academic researcher from Laboratory of Molecular Biology. The author has contributed to research in topics: Efflux & Minimum inhibitory concentration. The author has an hindex of 22, co-authored 122 publications receiving 1614 citations.
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Journal ArticleDOI
Evaluation of antibacterial and enhancement of antibiotic action by the flavonoid kaempferol 7-O-β-D-(6″-O-cumaroyl)-glucopyranoside isolated from Croton piauhiensis müll
B.G. Cruz,Hélcio Silva dos Santos,Paulo Nogueira Bandeira,Tigressa Helena Soares Rodrigues,Maria Geysillene Castro Matos,Mariana Ferreira do Nascimento,Guilherme G.C. de Carvalho,Raimundo Braz-Filho,Alexandre Magno Rodrigues Teixeira,Saulo R. Tintino,Henrique Douglas Melo Coutinho +10 more
TL;DR: The combination of the flavonoid with the aminoglycosides may be an alternative to potentiate the expected results in treatment against S. aureus and E. coli, since their association leads to a synergistic effect, reducing the MIC of these drugs and decreasing the dose necessary for therapeutic success.
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GC-MS-FID and potentiation of the antibiotic activity of the essential oil of Baccharis reticulata (ruiz & pav.) pers. and α-pinene
Priscilla Ramos Freitas,Ana Carolina Justino de Araújo,Cristina Rodrigues dos Santos Barbosa,Débora Feitosa Muniz,Ana Cristina Albuquerque da Silva,Janaína Esmeraldo Rocha,Cícera Datiane de Morais Oliveira-Tintino,Jaime Ribeiro-Filho,Luiz Everson da Silva,Camila Confortin,Wanderlei do Amaral,Cícero Deschamps,José Maria Barbosa-Filho,Natanael Teles Ramos de Lima,Saulo R. Tintino,Henrique Douglas Melo Coutinho +15 more
TL;DR: The authors conclude that the essential oil of B. reticulata, as well as the compound α-pinene, have antibacterial and antibiotic-modulating activities that make them useful in the development of new weapons against bacterial resistance.
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Cytoprotective effect of Eugenia uniflora L. against the waste contaminant mercury chloride
Francisco Assis Bezerra da Cunha,Antonio Ivanildo Pinho,Joycy Francely Sampaio dos Santos,Celestina E. Sobral-Souza,Rosimeire S. Albuquerque,Edinardo F.F. Matias,Nadghia Figueiredo Leite,Saulo R. Tintino,José Galberto Martins da Costa,Aline Augusti Boligon,Emily Pansera Waczuk,João Rocha,Thaís Posser,Henrique Douglas Melo Coutinho,Lucindo José Quintans-Júnior,Jeferson Luis Franco +15 more
TL;DR: The phytocompounds in the ethanol extract of E. uniflora could be interesting agents to protect different organisms against the heavy metal damages by a chelating or an antioxidative mechanism.
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Effect of Carvacrol and Thymol on NorA efflux pump inhibition in multidrug-resistant (MDR) Staphylococcus aureus strains.
Cristina Rodrigues dos Santos Barbosa,Jackelyne Roberta Scherf,Thiago Sampaio de Freitas,Irwin Rose Alencar de Menezes,Raimundo Luiz Silva Pereira,Joycy Francely Sampaio dos Santos,Sarah Silva Patrício de Jesus,Thais Pereira Lopes,Zildene de Sousa Silveira,Cícera Datiane de Morais Oliveira-Tintino,José Pinto de Siqueira Júnior,Henrique Douglas Melo Coutinho,Saulo R. Tintino,Francisco Assis Bezerra da Cunha +13 more
TL;DR: In this article, Carvacrol and Thymol terpenes were evaluated as possible Efflux Pump Inhibitors (EPIs) by determining the Minimum Inhibitory Concentration (MIC) and the association of these compounds in subinhibitory concentrations with the antibiotic Norfloxacin and with Ethidium Bromide (EtBr) against strains SA-1199 (wild-type) and SA- 1199B (overexpresses NorA) of Staphylococcus aureus.
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Anti-Candida activity of Mentha arvensis and Turnera ulmifolia
Karla K.A. Santos,Edinardo F.F. Matias,Celestina E.S. Souza,Saulo R. Tintino,Maria Flaviana Bezerra Morais Braga,Gláucia M.M. Guedes,Lavouisier F B Nogueira,Edson C Morais,José Galberto Martins da Costa,Irwin Rose Alencar de Menezes,Henrique Douglas Melo Coutinho +10 more
TL;DR: Ethanol extracts from M. arvensis and T. ulmifolia could represent a source of natural products with modifying antifungal activity and a potentiation effect was observed when the extracts were applied with metronidazole against C. tropicalis.