S
Scott D. Newsome
Researcher at Johns Hopkins University
Publications - 142
Citations - 4789
Scott D. Newsome is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Medicine & Multiple sclerosis. The author has an hindex of 29, co-authored 116 publications receiving 3610 citations. Previous affiliations of Scott D. Newsome include Johns Hopkins University School of Medicine & Kennedy Krieger Institute.
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Journal ArticleDOI
Optical coherence tomography segmentation reveals ganglion cell layer pathology after optic neuritis
Stephanie B. Syc,Shiv Saidha,Scott D. Newsome,John N. Ratchford,Michael J. Levy,E’Tona Ford,Ciprian M. Crainiceanu,Mary K Durbin,Jonathan D. Oakley,Scott A. Meyer,Elliot M. Frohman,Peter A. Calabresi +11 more
TL;DR: Results from this in vivo longitudinal study demonstrate retinal neuronal layer thinning following acute optic neuritis, corroborating the hypothesis that axonal injury may cause neuronal pathology in multiple sclerosis and suggesting the potential utility of quantitative optical coherence tomography retinal layer segmentation to monitor neuroprotective effects of novel agents in therapeutic trials.
Journal ArticleDOI
Primary retinal pathology in multiple sclerosis as detected by optical coherence tomography
Shiv Saidha,Stephanie B. Syc,Mohamed Ibrahim,Christopher Eckstein,Christina V. Warner,Sheena K. Farrell,Jonathan D. Oakley,Mary K Durbin,Scott A. Meyer,Laura J. Balcer,Elliot M. Frohman,Jason M. Rosenzweig,Scott D. Newsome,John N. Ratchford,Quan Dong Nguyen,Peter A. Calabresi +15 more
TL;DR: Findings support the possibility of primary retinal pathology in a subset of patients with multiple sclerosis in whom there appears to be disproportionate thinning of the inner and outer nuclear layers, which may be occurring as a primary process independent of optic nerve pathology.
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Optical Coherence Tomography Reflects Brain Atrophy in Multiple Sclerosis: A Four-Year Study
Shiv Saidha,Omar Al-Louzi,John N. Ratchford,Pavan Bhargava,Jiwon Oh,Scott D. Newsome,Jerry L. Prince,Dzung L. Pham,Dzung L. Pham,Snehashis Roy,Snehashis Roy,Peter C.M. van Zijl,Laura J. Balcer,Elliot M. Frohman,Daniel S. Reich,Daniel S. Reich,Ciprian M. Crainiceanu,Peter A. Calabresi +17 more
TL;DR: The aim of this work was to determine whether atrophy of specific retinal layers and brain substructures are associated over time, in order to further validate the utility of optical coherence tomography (OCT) as an indicator of neuronal tissue damage in patients with multiple sclerosis.
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Revised Recommendations of the Consortium of MS Centers Task Force for a Standardized MRI Protocol and Clinical Guidelines for the Diagnosis and Follow-Up of Multiple Sclerosis
Anthony Traboulsee,Jack H. Simon,Lael Stone,Elizabeth Fisher,David E. Jones,Ajay Malhotra,Scott D. Newsome,Jiwon Oh,Daniel S. Reich,Nancy Richert,Kottil Rammohan,Omar Khan,E. W. Radue,Corey C. Ford,June Halper,David K.B. Li +15 more
TL;DR: Suggestions for MR imaging protocols are given for the brain, for surveillance imaging for progressive multifocal leukoencephalopathy, for spinal cord imaging, and for the orbit, from an international group of neurologists and radiologists.
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Microcystic macular oedema, thickness of the inner nuclear layer of the retina, and disease characteristics in multiple sclerosis: a retrospective study
Shiv Saidha,Elias S. Sotirchos,Mohamed Ibrahim,Ciprian M. Crainiceanu,Jeffrey M. Gelfand,Yasir J. Sepah,John N. Ratchford,Jiwon Oh,Michaela A. Seigo,Scott D. Newsome,Laura J. Balcer,Elliot M. Frohman,Ari J. Green,Quan Dong Nguyen,Peter A. Calabresi +14 more
TL;DR: Increased baseline INL thickness in patients with MS was associated with the development of contrast-enhancing lesions and new T2 lesions, and relapses in Patients with relapsing-remitting MS during follow-up.