L
Laura J. Balcer
Researcher at New York University
Publications - 374
Citations - 20258
Laura J. Balcer is an academic researcher from New York University. The author has contributed to research in topics: Optic neuritis & Medicine. The author has an hindex of 69, co-authored 333 publications receiving 16843 citations. Previous affiliations of Laura J. Balcer include Yeshiva University & University of Pennsylvania.
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Journal ArticleDOI
Defining the clinical course of multiple sclerosis: The 2013 revisions
Fred D. Lublin,Stephen C. Reingold,Jeffrey A. Cohen,Gary Cutter,Per Soelberg Sørensen,Alan J. Thompson,Jerry S. Wolinsky,Laura J. Balcer,Brenda Banwell,Frederik Barkhof,Bruce F. Bebo,Peter A. Calabresi,Michel Clanet,Giancarlo Comi,Robert J. Fox,Mark S. Freedman,Andrew D. Goodman,Matilde Inglese,Ludwig Kappos,Bernd C. Kieseier,John A. Lincoln,Catherine Lubetzki,Aaron E. Miller,Xavier Montalban,Paul O'Connor,John Petkau,Carlo Pozzilli,Richard A. Rudick,Maria Pia Sormani,Olaf Stüve,Emmanuelle Waubant,Chris H. Polman +31 more
TL;DR: Refined descriptors that include consideration of disease activity (based on clinical relapse rate and imaging findings) and disease progression are proposed and strategies for future research to better define phenotypes are outlined.
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Relation of Visual Function to Retinal Nerve Fiber Layer Thickness in Multiple Sclerosis
Jennifer B. Fisher,Dina A. Jacobs,Clyde E. Markowitz,Steven L. Galetta,Nicholas J. Volpe,M. Ligia Nano-Schiavi,Monika Baier,Elliot M. Frohman,Heather Winslow,Teresa C. Frohman,Peter A. Calabresi,Maureen G. Maguire,Gary Cutter,Laura J. Balcer +13 more
TL;DR: Scores for low-contrast letter acuity and contrast sensitivity correlate well with RNFL thickness as a structural biomarker, supporting validity for these visual function tests as secondary clinical outcome measures for MS trials.
Journal ArticleDOI
Retinal nerve fiber layer is associated with brain atrophy in multiple sclerosis
Eliza Gordon-Lipkin,B. Chodkowski,Daniel S. Reich,Seth A. Smith,Mathew Pulicken,Laura J. Balcer,Elliot M. Frohman,Gary Cutter,Peter A. Calabresi +8 more
TL;DR: In multiple sclerosis (MS), retinal nerve fiber layer thickness is associated with brain parenchymal fraction and CSF volume, and quantification of axonal thickness in the retina by optical coherence tomography (OCT) provides concurrent information about MRI brain abnormality in MS.
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Longitudinal study of vision and retinal nerve fiber layer thickness in multiple sclerosis.
Lauren S. Talman,Esther R. Bisker,David J. Sackel,David A. Long,Kristin M. Galetta,John N. Ratchford,Deacon J. Lile,Sheena K. Farrell,Michael J. Loguidice,Gina Remington,Amy Conger,Teresa C. Frohman,Dina A. Jacobs,Clyde E. Markowitz,Gary Cutter,Gui-Shuang Ying,Yang Dai,Maureen G. Maguire,Steven L. Galetta,Elliot M. Frohman,Peter A. Calabresi,Laura J. Balcer +21 more
TL;DR: Cross‐sectional studies of optical coherence tomography show that retinal nerve fiber layer thickness is reduced in multiple sclerosis (MS) and correlates with visual function, and how longitudinal changes in RNFL thickness relate to visual loss is determined.
Journal ArticleDOI
Pegylated interferon beta-1a for relapsing-remitting multiple sclerosis (ADVANCE): a randomised, phase 3, double-blind study
Peter A. Calabresi,Bernd C. Kieseier,Douglas L. Arnold,Laura J. Balcer,Alexey Boyko,Jean Pelletier,Shifang Liu,Ying Zhu,Ali Seddighzadeh,Serena Hung,Aaron Deykin +10 more
TL;DR: After 48 weeks, peginterferon beta-1a significantly reduced relapse rate compared with placebo, suggesting the drug might be an effective treatment for relapsing-remitting multiple sclerosis with less frequent administration than available treatments.