Shiv Saidha

TL;DR: The recommendations will make reporting of quantitative OCT studies more consistent and in line with existing standards for reporting research in other biomedical areas and represent Class IV evidence.

TL;DR: Results from this in vivo longitudinal study demonstrate retinal neuronal layer thinning following acute optic neuritis, corroborating the hypothesis that axonal injury may cause neuronal pathology in multiple sclerosis and suggesting the potential utility of quantitative optical coherence tomography retinal layer segmentation to monitor neuroprotective effects of novel agents in therapeutic trials.

TL;DR: Findings support the possibility of primary retinal pathology in a subset of patients with multiple sclerosis in whom there appears to be disproportionate thinning of the inner and outer nuclear layers, which may be occurring as a primary process independent of optic nerve pathology.

TL;DR: The aim of this work was to determine whether atrophy of specific retinal layers and brain substructures are associated over time, in order to further validate the utility of optical coherence tomography (OCT) as an indicator of neuronal tissue damage in patients with multiple sclerosis.

TL;DR: Increased baseline INL thickness in patients with MS was associated with the development of contrast-enhancing lesions and new T2 lesions, and relapses in Patients with relapsing-remitting MS during follow-up.