S
Seiichiro Ogawa
Researcher at Keio University
Publications - 397
Citations - 4902
Seiichiro Ogawa is an academic researcher from Keio University. The author has contributed to research in topics: Total synthesis & Hydroxymethyl. The author has an hindex of 31, co-authored 370 publications receiving 4730 citations. Previous affiliations of Seiichiro Ogawa include Meisei University.
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Total Synthesis of Trehalase Inhibitor, Trehazolin.
Seiichiro Ogawa,Chikara Uchida +1 more
TL;DR: The total synthesis of trehalase inhibitor, trehazolin has been accomplished by coupling the optically active aminocyclopentanepentaol with α-D-glucopyranosylisothiocyanate derivative, followed by subsequent oxazoline-ring formation and removal of the protecting groups, thereby confirming its absolute configuration as mentioned in this paper.
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Total synthesis of (+)-asteltoxin1
TL;DR: A total synthesis of (+)-aste1toxin, a novel mycotoxin isolated from Aspergillus stellatus, has been achieved by using D-glucose as an enantiomerically pure starting material as mentioned in this paper.
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Concise syntheses of potent chaperone drug candidates, N-octyl-4-epi-β-valinenamine (NOEV) and its 6-deoxy derivative, from (+)-proto-quercitol.
TL;DR: Enzyme inhibition assays demonstrated that 6-deoxy NOEV possessed stronger inhibitory activity than the parent 1a, suggesting that the C-6 position of the 4-epi-β-valienamine-type inhibitor could have hydrophobic interactions at the β-galactosidase active site residues.
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