S
Serge L. Beaucage
Researcher at Food and Drug Administration
Publications - 99
Citations - 10663
Serge L. Beaucage is an academic researcher from Food and Drug Administration. The author has contributed to research in topics: Phosphoramidite & Deoxyribonucleoside. The author has an hindex of 34, co-authored 92 publications receiving 10426 citations. Previous affiliations of Serge L. Beaucage include Center for Drug Evaluation and Research & Westport Innovations.
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Large-Scale Preparation of the Sulfur-Transfer Reagent 3H-1,2- Benzodithiol-3-one 1,1-Dioxide.
TL;DR: In this paper, a large scale preparation of the SULFUR-TRANSFER REAGENT 3H-1,2-BENZODITHIOL-3-ONE 1,1-DIOXIDE is described.
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Protection of the 2′-Hydroxy Function of Ribonucleosides as an Iminooxymethyl Propanoate and Its 2′-O-Deprotection through an Intramolecular Decarboxylative Elimination Process
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N‐Trifluoroacetylamino Alcohols as Phosphodiester Protecting Groups in the Synthesis of Oligodeoxyribonucleotides.
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The 4‐Methylthio‐1‐Butyl Group for Phosphate/Thiophosphate Protection in Oligodeoxyribonucleotide Synthesis
TL;DR: The detailed preparation of deoxyribonucleoside phosphoramidites functionalized with a 4‐methylthio‐1‐butyl group for P(III) protection is described, along with the incorporation of these phosphor amidites into DNA oligonucleotides via solid‐phase techniques.
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