S
Sergio J. Gadaleta
Researcher at Rutgers University
Publications - 9
Citations - 983
Sergio J. Gadaleta is an academic researcher from Rutgers University. The author has contributed to research in topics: Infrared microscopy & Fourier transform infrared spectroscopy. The author has an hindex of 7, co-authored 9 publications receiving 941 citations. Previous affiliations of Sergio J. Gadaleta include Florida State University College of Arts and Sciences.
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Journal ArticleDOI
Fourier transform infrared microspectroscopic analysis of bones of osteocalcin-deficient mice provides insight into the function of osteocalcin
Adele L. Boskey,Sergio J. Gadaleta,Caren M. Gundberg,S. B. Doty,Patricia Ducy,Gerard Karsenty +5 more
TL;DR: Test the hypothesis that, in addition to regulating osteoblastic activity, osteocalcin is involved in regulating mineral properties, a more sensitive assay of mineralization was used and spatially resolved data provide evidence that osteoccin is required to stimulate bone mineral maturation.
Journal ArticleDOI
Fourier transform infrared spectroscopy of the solution-mediated conversion of amorphous calcium phosphate to hydroxyapatite: New correlations between X-ray diffraction and infrared data
TL;DR: It is suggested that a combination of second-derivative and curve-fitting analysis of the ν1, ν3 phosphate contour allows the most reproducible evaluation of these spectra.
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Characterization of biological samples by two-dimensional infrared spectroscopy: Simulation of frequency, bandwidth, and intensity changes
TL;DR: In this article, the effects of frequency and bandwidth changes on 2D IR spectra were simulated and it was shown that when bandwidth changes are coupled with either frequency shifts and/or intensity changes, the effect of the bandwidth change is reduced.
Journal ArticleDOI
Fourier transform infrared microscopy of calcified turkey leg tendon.
TL;DR: The power of FT-IRMS to monitor spatial variations of the Mineral phase in calcified tissue and the incorporation of polarized radiation provides a method capable of assessing the molecular orientation of the mineral phase relative to the collagen matrix are demonstrated.
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Polarized FT-IR microscopy of calcified turkey leg tendon.
TL;DR: The ability of polarized FT-IRM to assess the orientation of the mineral and matrix components of calcified tissue at the microscopic level is demonstrated, indicating that aging produces a more highly oriented mineral.