S
Seung Il Kim
Researcher at Washington University in St. Louis
Publications - 129
Citations - 5503
Seung Il Kim is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Bacterial outer membrane & Cancer. The author has an hindex of 29, co-authored 108 publications receiving 4011 citations. Previous affiliations of Seung Il Kim include University of California, San Francisco & University of Southern California.
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Journal ArticleDOI
Rapid Detection of COVID-19 Causative Virus (SARS-CoV-2) in Human Nasopharyngeal Swab Specimens Using Field-Effect Transistor-Based Biosensor.
Giwan Seo,Geonhee Lee,Mi-Jeong Kim,Seung Hwa Baek,Minsuk Choi,Keun Bon Ku,Chang-Seop Lee,Sangmi Jun,Daeui Park,Hong Gi Kim,Seong-Jun Kim,Jeong O. Lee,Bum Tae Kim,Edmond Changkyun Park,Seung Il Kim +14 more
TL;DR: The FET sensor fabricated here is a highly sensitive immunological diagnostic method for COVID-19 that requires no sample pretreatment or labeling and is a promising FET biosensor for SARS-CoV-2.
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Sensory Neuron-Specific GPCR Mrgprs Are Itch Receptors Mediating Chloroquine-Induced Pruritus
Qin Liu,Zongxiang Tang,Lenka Surdenikova,Seung Il Kim,Kush N. Patel,Andrew Kim,Fei Ru,Yun Guan,Hao Jui Weng,Yixun Geng,Bradley J. Undem,Marian Kollarik,Zhou-Feng Chen,David J. Anderson,David J. Anderson,Xinzhong Dong,Xinzhong Dong +16 more
TL;DR: It is shown that Mrgprs, a family of G protein-coupled receptors expressed exclusively in peripheral sensory neurons, function as itch receptors and may provide molecular access to itch-selective neurons and constitute novel targets for itch therapeutics.
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Development of Reverse Transcription Loop-Mediated Isothermal Amplification Assays Targeting Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
TL;DR: R reverse transcription loop-mediated isothermal amplification (RT-LAMP) assays are developed and evaluated to detect genomic RNA of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative virus of COVID-19.
Journal ArticleDOI
Unidirectional Cross-Activation of GRPR by MOR1D Uncouples Itch and Analgesia Induced by Opioids
Xian-Yu Liu,Zhongchun Liu,Yan-Gang Sun,Michael H. Ross,Seung Il Kim,Feng-Fang Tsai,Qi Fang Li,Joseph Jeffry,Ji-Young Kim,Horace H. Loh,Zhou-Feng Chen +10 more
TL;DR: It is suggested that opioid-induced itch is an active process concomitant with but independent of opioid analgesia, occurring via the unidirectional cross-activation of GRPR signaling by MOR1D heterodimerization.
Journal ArticleDOI
Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram-negative bacterial outer membrane
Jeong Soon Park,Woo Cheol Lee,Kwon Joo Yeo,Kyoung-Seok Ryu,Malika Kumarasiri,Dusan Hesek,Mijoon Lee,Shahriar Mobashery,Jung Hyun Song,Seung Il Kim,Je Chul Lee,Chaejoon Cheong,Young Ho Jeon,Hye-Yeon Kim +13 more
TL;DR: An NMR‐based computational model for complexation between the PGN and OmpA emerged, and this model is validated by determining the crystal structure in complex with a synthetic PGN fragment.