S
Shaden Kamhawi
Researcher at National Institutes of Health
Publications - 150
Citations - 9589
Shaden Kamhawi is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Leishmania & Leishmania major. The author has an hindex of 47, co-authored 142 publications receiving 8556 citations. Previous affiliations of Shaden Kamhawi include Oswaldo Cruz Foundation & Government of the United States of America.
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Journal ArticleDOI
Gut Microbiota Egested During Bites of Infected Sand flies Augments Severity of Leishmaniasis via Inflammasome-Derived IL-1β
Ranadhir Dey,Amritanshu B. Joshi,Fabiano Oliveira,Lais Pereira,Anderson B. Guimarães-Costa,Tiago D. Serafim,Waldionê de Castro,Iliano V. Coutinho-Abreu,Parna Bhattacharya,Shannon Townsend,Hamide Aslan,Alec Perkins,Claudio Meneses,Robert Duncan,Hira L. Nakhasi,Jesus G. Valenzuela,Shaden Kamhawi +16 more
Posted ContentDOI
Preclinical validation of a second generation leishmanization vaccine against vector transmitted fatal visceral leishmaniasis
Hira L. Nakhasi,Ranadhir Dey,Sreenivas Gannavaram,Subhradip Karmakar,Parna Bhattacharya,Nevien Ismail,Abhay R. Satoskar,Greta Volpedo,Oliveira Lf,James Oristian,Claudio Meneses,Jesus G. Valenzuela,Shaden Kamhawi,Wenmin Zhang,Greg Matlashewski,Shinjiro Hamano,Monika Satoskar,Sanika Satoskar,Sastry Rm,Swarnendu Kaviraj,Suchita Singh,Krishna Pal Singh,Sushmita Das,Pradeep Das,Mondal A,Krishna Pandey +25 more
TL;DR: This study demonstrates that the LmCen−/− parasites are safe and efficacious against VL and it is a strong candidate vaccine to be tested in a human clinical trial.
Posted ContentDOI
Distinct gene expression patterns in vector-residing Leishmania infantum identify parasite stage-enriched markers
Iliano V. Coutinho-Abreu,Tiago D. Serafim,Claudio Meneses,Shaden Kamhawi,Fabiano Oliveira,Jesus G. Valenzuela +5 more
TL;DR: Using the transcriptional signatures exhibited by distinct Leishmania stages during their development in the sand fly midgut, genes predominantly enriched in each stage are determined and a repertoire of stage-specific markers for further development are provided as molecular tools for epidemiological studies.
Journal ArticleDOI
Coinfection with Trypanosoma brucei confers protection against cutaneous leishmaniasis
Lais Pereira,Fabiano Oliveira,Shannon Townsend,Sonia Metangmo,Claudio Meneses,Ian N. Moore,Cláudia Brodskyn,Jesus G. Valenzuela,Stefan Magez,Shaden Kamhawi +9 more
TL;DR: The results revealed that infection with T. b.
Journal ArticleDOI
Antibody Responses to Phlebotomus papatasi Saliva in American Soldiers With Cutaneous Leishmaniasis Versus Controls
Naomi E. Aronson,Fabiano Luiz de Oliveira,Regis Gomes,William Porter,Robin S. Howard,Shaden Kamhawi,Jesus G. Valenzuela +6 more
TL;DR: Compared sand fly saliva-specific human IgG levels and recognized antigens between the two groups, MW30 was the most frequently recognized antigen suggesting a role as biomarker for sand fly exposure and CL risk and anti-Ph.