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Shahid Hameed

Researcher at Quaid-i-Azam University

Publications -  182
Citations -  2500

Shahid Hameed is an academic researcher from Quaid-i-Azam University. The author has contributed to research in topics: Ring (chemistry) & Aryl. The author has an hindex of 24, co-authored 164 publications receiving 1989 citations. Previous affiliations of Shahid Hameed include Chinese Academy of Sciences.

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Synthesis, antioxidant activities and urease inhibition of some new 1,2,4-triazole and 1,3,4-thiadiazole derivatives.

TL;DR: N-(2,4-Dimethylphenyl)-5-(4-nitrophenyl)-1,3, 4-thiadiazol-2-amine (9h) showed excellent antioxidant activity more than the standard drug whereas 4,5-disubstituted-2,8-dihydro-3H-1,2-4-triazole-3-thione exhibited potent urease inhibitory activities.
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In vitro antitumor and antiviral activities of new benzothiazole and 1,3,4-oxadiazole-2-thione derivatives

TL;DR: The title compounds were tested against representatives of several virus families containing single stranded RNA genomes and against double-stranded RNA genomes, as well as some Flaviviridae viruses, and showed strong effects on leukaemia cell lines CCRF-CEM.
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Synthesis and anti‐HIV activity of new chiral 1,2,4‐triazoles and 1,3,4‐thiadiazoles

TL;DR: In this article, the authors used hydrazides with 4-chlorophenylisothiocyanate in MeOH to synthesize 4.5-substituted 4-(4-chlorophenylamino)-4H-1,2,4-triazol-3-thiones 3 and 2.
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Exploiting the Role of Molecular Electrostatic Potential, Deformation Density, Topology, and Energetics in the Characterization of S···N and Cl···N Supramolecular Motifs in Crystalline Triazolothiadiazoles

TL;DR: In this paper, a detailed analysis of the molecular and crystal packing of a series of pharmaceutically active triazolothiadiazole derivatives is reported, showing the presence of inversion dimers due to the formation of strong S···N chalcogen bonds.
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Design, synthesis, and urease inhibition studies of some 1,3,4-oxadiazoles and 1,2,4-triazoles derived from mandelic acid.

TL;DR: Some new structural type inhibitors of urease were synthesized in two steps from mandelic acid hydrazides and aryl isothiocyantes and may be subjected to further investigations for the development of antiulcer drugs.