S
Shannon G. Matta
Researcher at University of Tennessee Health Science Center
Publications - 69
Citations - 4257
Shannon G. Matta is an academic researcher from University of Tennessee Health Science Center. The author has contributed to research in topics: Nicotine & Nicotinic agonist. The author has an hindex of 34, co-authored 69 publications receiving 4099 citations. Previous affiliations of Shannon G. Matta include University of Minnesota & Rutgers University.
Papers
More filters
Journal ArticleDOI
Guidelines on nicotine dose selection for in vivo research
Shannon G. Matta,David J.K. Balfour,Neal L. Benowitz,R. Thomas Boyd,Jerry J. Buccafusco,Anthony R. Caggiula,Caroline R. Craig,Allan C. Collins,M. Imad Damaj,Eric C. Donny,Phillip S. Gardiner,Sharon R. Grady,Ulrike Heberlein,Sherry Leonard,Edward D. Levin,Ronald J. Lukas,Athina Markou,Michael J. Marks,Sarah E. McCallum,Neeraja Parameswaran,Kenneth A. Perkins,Marina R. Picciotto,Maryka Quik,Jed E. Rose,Adrian Rothenfluh,William R Schafer,Ian P. Stolerman,Rachel F. Tyndale,Jeanne M. Wehner,Jeffrey M. Zirger +29 more
TL;DR: A new, experimentally based compilation of species-specific dose selection for studies on the in vivo effects of nicotine, addressing issues related to genetic background, age, acute vs chronic exposure, route of administration, and behavioral responses is provided.
Journal ArticleDOI
Tumor Necrosis Factor-α is a Potent ACTH Secretagogue: Comparison to Interleukin-1β
TL;DR: Human rTNF, administered at doses (100-1000 ng) which failed to affect blood pressure, food consumption or prolactin levels, resulted in significant peak elevations of rat plasma ACTH within 20 min, compared to 53 ± 16 pg/ml for vehicle.
Journal ArticleDOI
Regulation of the messenger ribonucleic acid for corticotropin-releasing factor in the paraventricular nucleus and other brain sites of the rat
TL;DR: It is concluded that the same sized mRNA for CRF is synthesized in the PVN, BN, CN, and SON, but only the PV N mRNA responds to alterations of peripheral glucocorticoid status, which may imply that only CRF from the PVn is involved in control of the hypothalamic-pituitary-adrenal axis.
Journal ArticleDOI
Self-administration in rats allowed unlimited access to nicotine
TL;DR: An animal model of nicotine self-administration is developed in rats that acquired the behavior while having virtually unlimited access to injections of a relatively low dose of the drug; the rats did not have any prior operant training or shaping.
Journal ArticleDOI
Response of the hypothalamo-pituitary-adrenal axis to nicotine.
TL;DR: Data are presented demonstrating that nicotine acts via a central mechanism to stimulate indirectly the release of ACTH from the anterior pituitary corticotropes, and the desensitization characteristics of the neuroendocrine responses to both acute and chronic nicotine exposure are indicative of an alteration in these NAchRs.