Caroline R. Craig

TL;DR: A new, experimentally based compilation of species-specific dose selection for studies on the in vivo effects of nicotine, addressing issues related to genetic background, age, acute vs chronic exposure, route of administration, and behavioral responses is provided.

TL;DR: The HSN neurons play a central role in driving egg-laying behavior through direct excitation of the vulval muscles and VC motor neurons, and the HSNs are active in the absence of synaptic input, suggesting that egg laying may be controlled through modulation of autonomous HSN activity.

TL;DR: The p38 mitogen‐activated protein kinase (MAPK) cascade is an evolutionarily conserved signalling mechanism involved in processes as diverse as apoptosis, cell fate determination, immune function and stress response and Aberrant p38 signalling has been implicated in many human diseases.

TL;DR: The results indicate that Dpp pathway activity is tightly regulated across time in the pupal retina and that epithelial cells in this tissue require Dpp signaling to achieve their correct shape and position within the ommatidial hexagon, and point to the Dpp pathways as a third component and functional link between two adhesion systems, Hibris-Roughest and DE-cadherin.

TL;DR: The removal of obsolete cells and tissues, the elimination of aberrant, potentially harmful cells, and the sculpting and maintenance of tissue architecture in Drosophila retina are described.