U
Ulrike Heberlein
Researcher at Howard Hughes Medical Institute
Publications - 114
Citations - 11629
Ulrike Heberlein is an academic researcher from Howard Hughes Medical Institute. The author has contributed to research in topics: Drosophila melanogaster & Gene. The author has an hindex of 59, co-authored 114 publications receiving 10841 citations. Previous affiliations of Ulrike Heberlein include University of California, Berkeley & Baylor College of Medicine.
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Journal ArticleDOI
Guidelines on nicotine dose selection for in vivo research
Shannon G. Matta,David J.K. Balfour,Neal L. Benowitz,R. Thomas Boyd,Jerry J. Buccafusco,Anthony R. Caggiula,Caroline R. Craig,Allan C. Collins,M. Imad Damaj,Eric C. Donny,Phillip S. Gardiner,Sharon R. Grady,Ulrike Heberlein,Sherry Leonard,Edward D. Levin,Ronald J. Lukas,Athina Markou,Michael J. Marks,Sarah E. McCallum,Neeraja Parameswaran,Kenneth A. Perkins,Marina R. Picciotto,Maryka Quik,Jed E. Rose,Adrian Rothenfluh,William R Schafer,Ian P. Stolerman,Rachel F. Tyndale,Jeanne M. Wehner,Jeffrey M. Zirger +29 more
TL;DR: A new, experimentally based compilation of species-specific dose selection for studies on the in vivo effects of nicotine, addressing issues related to genetic background, age, acute vs chronic exposure, route of administration, and behavioral responses is provided.
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Mushroom body output neurons encode valence and guide memory-based action selection in Drosophila
Yoshinori Aso,Divya Sitaraman,Toshiharu Ichinose,Karla R. Kaun,Katrin Vogt,Ghislain Belliart-Guérin,Pierre-Yves Plaçais,Alice A. Robie,Nobuhiro Yamagata,Christopher Schnaitmann,William J Rowell,Rebecca M. Johnston,Teri T.B. Ngo,Nan Chen,Wyatt Korff,Michael N. Nitabach,Ulrike Heberlein,Thomas Preat,Kristin Branson,Hiromu Tanimoto,Gerald M. Rubin +20 more
TL;DR: This work studied the role of MBONs in several associative learning tasks and in sleep regulation, revealing the extent to which information flow is segregated into distinct channels and suggesting possible roles for the multi-layered MBON network.
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Alpha-factor-directed synthesis and secretion of mature foreign proteins in Saccharomyces cerevisiae
Anthony J. Brake,James P Merryweather,Doris Coit,Ulrike Heberlein,Frank R. Masiarz,Guy T. Mullenbach,Mickey S. Urdea,Pablo Valenzuela,Philip J. Barr +8 more
TL;DR: Saccharomyces cerevisiae cells were transformed with plasmids containing hybrid genes in which the sequence encoding mature human epidermal growth factor was joined to sequences encoding the leader region (preprosegment) of the precursor of the yeast mating pheromone alpha-factor.
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Ethanol Intoxication in Drosophila: Genetic and Pharmacological Evidence for Regulation by the cAMP Signaling Pathway
TL;DR: Functional evidence is provided for the involvement of the cAMP signal transduction pathway in the behavioral response to intoxicating levels of ethanol in Drosophila.
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The TGFβ homolog dpp and the segment polarity gene hedgehog are required for propagation of a morphogenetic wave in the Drosophila retina
TL;DR: The results suggest that developing retinal cells drive the progression of morphogenesis utilizing the products of the hedgehog (hh) and decapentaplegic (dpp) genes.