Shanshan Li

TL;DR: In this paper, a single-atom nanozyme (SAzyme) based on a zinc-based zeolitic-imidazolate-framework (ZIF-8)-derived carbon nanomaterial containing atomically dispersed zinc atoms was investigated.

TL;DR: A novel nanozyme (PtFe@Fe3O4) with dual enzyme-like activities for highly efficient tumor catalytic therapy shows the intrinsic photothermal effect as well as photo-enhanced peroxidase-like and catalase- like activities in the acidic TME, thereby effectively killing tumor cells and overcoming the tumor hypoxia.

TL;DR: It is demonstrated that both IMSN and TI can regulate the tumor immune microenvironment, resulting in macrophage polarization from M2 to M1, and thus inducing the regeneration of H2O2, which can promote catalytic activities of IMSN nanozyme.

TL;DR: In vitro and in vivo studies indicate that the single-component H-Pd NSs can act as a photothermal/photodynamic agent for imaging-guided hypoxic tumor therapy, with a high tumor inhibition rate of 99.7%.

TL;DR: Results show that this IPTT is a safe and radical treatment for eradicating tumor cells, and may benefit future clinical pancreatic cancer patients, and the IPTT could also inhibit pancreatic tumor metastasis which can be harnessed for effective cancer immunotherapy.