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Sheng-Fan Wang
Researcher at Kaohsiung Medical University
Publications - 75
Citations - 1778
Sheng-Fan Wang is an academic researcher from Kaohsiung Medical University. The author has contributed to research in topics: Virus & Influenza A virus. The author has an hindex of 19, co-authored 67 publications receiving 1318 citations. Previous affiliations of Sheng-Fan Wang include University of California, Davis & National Yang-Ming University.
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Journal ArticleDOI
Antibody-dependent SARS coronavirus infection is mediated by antibodies against spike proteins
Sheng-Fan Wang,Sheng-Fan Wang,Sung-Pin Tseng,Chia-Hung Yen,Jyh Yuan Yang,Ching Han Tsao,Chun Wei Shen,Kuan Hsuan Chen,Fu-Tong Liu,Wu Tse Liu,Yi Ming Arthur Chen,Jason C. Huang +11 more
TL;DR: Quantitative-PCR and immunofluorescence staining results indicate that SARS-CoV is capable of replication in HL-CZ cells, and of displaying virus-induced cytopathic effects and increased levels of TNF-α, IL-4 and IL-6 two days post-infection, while data from infectivity assays indicate that antibodies against SARsCoV spike proteins may trigger ADE effects.
Journal ArticleDOI
Human-leukocyte antigen class I Cw 1502 and class II DR 0301 genotypes are associated with resistance to severe acute respiratory syndrome (SARS) infection.
Sheng-Fan Wang,Sheng-Fan Wang,Kuan Hsuan Chen,Marcelo Chen,Wen Yi Li,Yen Ju Chen,Ching Han Tsao,Muh Yong Yen,Jason C. Huang,Yi Ming Arthur Chen +9 more
TL;DR: A case-control study of the association of HLA with SARS revealed that the HLA-Cw1502 and DR0301 alleles conferred resistance against SARS infection (p<0.05).
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Simple Strategy for Rapid and Sensitive Detection of Avian Influenza A H7N9 Virus Based on Intensity-Modulated SPR Biosensor and New Generated Antibody
Ying Feng Chang,Wen Hung Wang,Yi Wei Hong,Ruei Yu Yuan,Kuan Hsuan Chen,Yu Wen Huang,Po-Liang Lu,Yen-Hsu Chen,Yi Ming Arthur Chen,Li Chen Su,Sheng-Fan Wang +10 more
TL;DR: The results of this study indicate that the proposed simple strategy using an intensity-modulated surface plasmon resonance (IM-SPR) biosensor integrated with a new generated monoclonal antibody demonstrates high sensitivity and time-saving in H7N9 virus detection.
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The role of galectins in virus infection - A systemic literature review.
Wen Hung Wang,Chih Yen Lin,Max R. Chang,Aspiro Nayim Urbina,Wanchai Assavalapsakul,Arunee Thitithanyanont,Yen-Hsu Chen,Fu-Tong Liu,Sheng-Fan Wang +8 more
TL;DR: Information is offered regarding the various roles galectins shown in viral infection and it is suggested that galectin can potentially be used as viral therapeutic targets or antagonists.
Journal ArticleDOI
DC-SIGN mediates avian H5N1 influenza virus infection in cis and in trans
Sheng-Fan Wang,Jason C. Huang,Yuan Ming Lee,Shih Jen Liu,Yu Jiun Chan,Yat Pang Chau,Pele Chong,Yi Ming Arthur Chen +7 more
TL;DR: DC-SIGN acts as a capture or attachment molecule for avian H5N1 virus, and DC-SIGN mediates infections in cis and in trans.