Shmuel Kivity

TL;DR: In patients with hereditary angioedema having acute attacks, a significant benefit of icatibant as compared with tranexamic acid in one trial and a nonsignificantbenefit of ic atibant in the other trial are found with regard to the primary end point.

TL;DR: In patients with hereditary angioedema, the prophylactic use of a subcutaneous C1 inhibitor twice weekly significantly reduced the frequency of acute attacks.

TL;DR: By modulating α-SM actin expression and exertion of the mitogenic effect on alveolar fibroblasts, ET-1 might play an important role in the fibrogenesis of ILD.

TL;DR: About 50% of patients with C1-INH-HAE type I or II have previously had their conditions misdiagnosed, most commonly as allergic angioedema or appendicitis, which results in marked delays in receiving the correct diagnosis.

TL;DR: Pulmonary function tests were performed at rest and following blood transfusion on 17 patients with thalassemia major and a significant drop was seen in arterial oxygen tension and in forced vital capacity.