S
Sho Yamasaki
Researcher at Osaka University
Publications - 195
Citations - 11586
Sho Yamasaki is an academic researcher from Osaka University. The author has contributed to research in topics: C-type lectin & Immune system. The author has an hindex of 45, co-authored 156 publications receiving 9894 citations. Previous affiliations of Sho Yamasaki include Chiba University & National Institute for Medical Research.
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Journal ArticleDOI
The effects of 5-OP-RU stereochemistry on its stability and MAIT-MR1 axis
Takuro Matsuoka,Chihiro Motozono,Akira Hattori,Hideaki Kakeya,Sho Yamasaki,Shinya Oishi,Hiroaki Ohno,Shinsuke Inuki +7 more
TL;DR: In this paper, the authors synthesized all stereoisomers of 5-OP-RU to investigate the effects of its stereochemistry on the MR1-dependent Mucosal-associated invariant T (MAIT) cell activation and MR1 upregulation.
Journal ArticleDOI
Water-soluble trehalose glycolipids show superior Mincle binding and signaling but impaired phagocytosis and IL-1β production
Matp Manthrirathna,Emma M. Dangerfield,Shigenari Ishizuka,Aodhamair Woods,Brenda S. Luong,Sho Yamasaki,Mattie S. M. Timmer,Bridget L. Stocker +7 more
TL;DR: In this article , a polyethylene glycol modified trehalose glycolipids (PEG-TGLs) with enhanced water solubility and strong murine Mincle (mMincle) binding and signaling was used as a proxy for adjuvanticity.
Posted ContentDOI
InterClone: Store, Search and Cluster Adaptive Immune Receptor Repertoires
Jan Wilamowski,Zichang Xu,Hendra S. Ismanto,Songling Li,Shunsuke Teraguchi,Mara Anais Llamas Covarrubias,Xiuyuan Lu,Sho Yamasaki,Daron M. Standley +8 more
TL;DR: The use of InterClone is illustrated with two recently reported examples: searching for Sars-CoV-2 infection-enhancing antibodies in bulk COVID-19 and healthy donor repertoires and identification of SARS-Cov-2 specific TCRs by clustering paired and bulk sequences from CO VID-19, BNT162b2 vaccinated and healthy unvaccinated donors.
Journal ArticleDOI
Necroptosis DAMPens anti-tumor immunity.
TL;DR: It is demonstrated that necroptosis induces PDA progression through the inhibition of anti-tumor immunity, which indicated that blockade of RIP3-mediated signaling changes the tumor microenvironment to unlock immune suppression status and results in tumor regression.
Journal ArticleDOI
A terpene nucleoside from M. tuberculosis induces lysosomal lipid storage in foamy macrophages
Melissa Bedard,Sanne van der Niet,Elliott M. Bernard,Gregory H. Babunovic,Tan-Yun Cheng,Beren Aylan,Anita E. Grootemaat,Sahadevan Raman,Laure Botella,Eri Ishikawa,Mary P. O'Sullivan,Seónadh O'Leary,Jacob A. Mayfield,Jeffrey Buter,Adriaan J. Minnaard,Sarah M. Fortune,Leon Murphy,Daniel S. Ory,Joseph Keane,Sho Yamasaki,Maximiliano G. Gutierrez,Nicole N. van der Wel,D. Branch Moody +22 more
TL;DR: In this article , a terpenyl nucleoside shed from Mycobacterium tuberculosis, 1-tuberculosinyladenosine (1-TbAd), caused lysosomal maturation arrest and autophagy blockade, leading to lipid storage in M1 macrophages.