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Sho Yamasaki

Researcher at Osaka University

Publications -  195
Citations -  11586

Sho Yamasaki is an academic researcher from Osaka University. The author has contributed to research in topics: C-type lectin & Immune system. The author has an hindex of 45, co-authored 156 publications receiving 9894 citations. Previous affiliations of Sho Yamasaki include Chiba University & National Institute for Medical Research.

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Macrophage-inducible C-type lectin underlies obesity-induced adipose tissue fibrosis

TL;DR: It is indicated that Mincle, when activated by an endogenous ligand released from dying adipocytes, is involved in adipose tissue remodelling, thereby suggesting that sustained interactions between adipocytes and macrophages within CLS could be a therapeutic target for obesity-induced ectopic lipid accumulation.
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Restoration of Pattern Recognition Receptor Costimulation to Treat Chromoblastomycosis, a Chronic Fungal Infection of the Skin

TL;DR: Results demonstrate how a failure in innate recognition can result in chronic infection, highlight the importance of coordinated PRR signaling, and provide proof of the principle that exogenously applied PRR agonists can be used therapeutically.
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Structural analysis for glycolipid recognition by the C-type lectins Mincle and MCL.

TL;DR: In this article, the crystal structures of Mincle, MCL and the Mincle-citric acid complex were reported, showing that these receptors are capable of interacting with sugar in a Ca2+-dependent manner, as observed in other C-type lectins.
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Notch-Hes1 pathway is required for the development of IL-17-producing γδ T cells.

TL;DR: It is shown that intrathymic development of the naturally occurring IL-17-producing γδ T cells is independent of STAT3 and partly dependent on RORγt, and Hes1, one of the basic helix-loop-helix proteins involved in Notch signaling, is critically involved in the development of IL- 17-producing Greek T cells.
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Evaluation of thermal properties of UO2 and PuO2 by equilibrium molecular dynamics simulations from 300 to 2000 K

TL;DR: In this paper, the thermal properties of UO2 and PuO2 were investigated by the equilibrium molecular dynamics simulations between 300 and 2000 K using the Born-Mayer-Huggins interatomic potential with the partially ionic model (PIM).