S
Shohreh Issazadeh-Navikas
Researcher at University of Copenhagen
Publications - 63
Citations - 8825
Shohreh Issazadeh-Navikas is an academic researcher from University of Copenhagen. The author has contributed to research in topics: T cell & Natural killer T cell. The author has an hindex of 23, co-authored 63 publications receiving 7228 citations. Previous affiliations of Shohreh Issazadeh-Navikas include Lund University.
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Journal ArticleDOI
Endogenous IFN-β signaling exerts anti-inflammatory actions in experimentally induced focal cerebral ischemia
Ana R. Inácio,Ana R. Inácio,Ana R. Inácio,Yawei Liu,Bettina Hjelm Clausen,Martina Svensson,Krzysztof Kucharz,Krzysztof Kucharz,Yiyi Yang,Totte Stankovich,Reza Khorooshi,Kate Lykke Lambertsen,Shohreh Issazadeh-Navikas,Tomas Deierborg +13 more
TL;DR: It is concluded that endogenous IFN-β signaling attenuates local inflammation, regulates peripheral immune cells, and, thereby, may contribute positively to stroke outcome.
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CD1d-Dependent NKT Cells Play a Protective Role in Acute and Chronic Arthritis Models by Ameliorating Antigen-Specific Th1 Responses
Anna Teige,Robert Bockermann,Robert Bockermann,Maruf Hasan,Katarina Olofsson,Yawei Liu,Yawei Liu,Shohreh Issazadeh-Navikas,Shohreh Issazadeh-Navikas +8 more
TL;DR: Support is provided for CD1d-dependent NKTs being suppressor cells in acute and chronic arthritis, likely via inhibition of arthritogenic Th1 cells, which makes CD1D-dependentNKTs an attractive target for therapeutic intervention.
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pDC therapy induces recovery from EAE by recruiting endogenous pDC to sites of CNS inflammation.
Fernanda V. Duraes,Carla Lippens,Karin Steinbach,Juan Dubrot,Dale Brighouse,Nathalie Bendriss-Vermare,Shohreh Issazadeh-Navikas,Doron Merkler,Stéphanie Hugues +8 more
TL;DR: It is shown that pDCs transferred during acute disease phase confer recovery from EAE, and this study may pave the way for novel pDC-based cell therapies in autoimmune diseases, aiming at specifically modulating pathogenic cells that induce and sustain autoimmune inflammation.
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Neuronal IFN-beta–induced PI3K/Akt-FoxA1 signalling is essential for generation of FoxA1 + T reg cells
Yawei Liu,Andrea Marin,Patrick Ejlerskov,Louise Munk Rasmussen,Marco Prinz,Shohreh Issazadeh-Navikas +5 more
TL;DR: It is shown that lack of neuronal IFNβ signalling is associated with the absence of programme death ligand-1 (PDL1), which prevents their ability to reprogramme Tenc cells to FoxA1+Tregs.
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Interferon-β-induced miR-1 alleviates toxic protein accumulation by controlling autophagy.
Camilla Nehammer,Patrick Ejlerskov,Sandeep Gopal,Ava Handley,Leelee Ng,Pedro Moreira,Huikyong Lee,Shohreh Issazadeh-Navikas,David C. Rubinsztein,Roger Pocock +9 more
TL;DR: It is reported that the microRNA miR-1 regulates the autophagy pathway through conserved targeting of the orthologous Tre-2/Bub2/CDC16 (TBC) Rab GTPase-activating proteins TBC-7 and TBC1D15 in Caenorhabditis elegans and mammalian cells, respectively.