S
Shoichi Masushige
Researcher at Tokyo University of Agriculture
Publications - 52
Citations - 6583
Shoichi Masushige is an academic researcher from Tokyo University of Agriculture. The author has contributed to research in topics: Retinoic acid & Gene expression. The author has an hindex of 25, co-authored 52 publications receiving 6309 citations.
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Journal ArticleDOI
Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase
Shigeaki Kato,Hideki Endoh,Yoshikazu Masuhiro,Takuya Kitamoto,Shimami Uchiyama,Haruna Sasaki,Shoichi Masushige,Yukiko Gotoh,Eisuke Nishida,Hiroyuki Kawashima,Daniel Metzger,Pierre Chambon +11 more
TL;DR: The phosphorylation of the human estrogen receptor (ER) serine residue at position 118 is required for full activity of the ER activation function 1 (AF-1), which is modulated by the phosphorylated Ser118 through the Ras-MAPK cascade of the growth factor signaling pathways.
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Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning
Tatsuya Yoshizawa,Yuki Handa,Yoshikatsu Uematsu,Shu Takeda,Keisuke Sekine,Yuko Yoshihara,Toru Kawakami,Kouki Arioka,Hiroshi Sato,Yasushi Uchiyama,Shoichi Masushige,Akiyoshi Fukamizu,Toshio Matsumoto,Shigeaki Kato +13 more
TL;DR: It is reported here that in VDR null mutant mice, no defects in development and growth were observed before weaning, irrespective of reduced expression of vitamin D target genes, which establishes a critical role for VDR in growth, bone formation and female reproduction in the post-weaning stage.
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Memory Reconsolidation and Extinction Have Distinct Temporal and Biochemical Signatures
Akinobu Suzuki,Sheena A. Josselyn,Sheena A. Josselyn,Paul W. Frankland,Paul W. Frankland,Shoichi Masushige,Alcino J. Silva,Satoshi Kida +7 more
TL;DR: The temporal dynamics of memory reconsolidation are dependent on the strength and age of the memory, such that younger and weaker memories are more easily reconsolidated than older and stronger memories.
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CREB required for the stability of new and reactivated fear memories
Satoshi Kida,Sheena A. Josselyn,Sandra Penña De Ortiz,Jeffrey H. Kogan,Itzamarie Chevere,Shoichi Masushige,Alcino J. Silva +6 more
TL;DR: It is found that CREB is crucial for the consolidation of long-term conditioned fear memories, but not for encoding, storage or retrieval of these memories.
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A far upstream estrogen response element of the ovalbumin gene contains several half-palindromic 5′-TGACC-3′ motifs acting synergistically
TL;DR: An estrogen-responsive enhancer element (DH3 ERE) in the estrogen-induced DNAase I-hypersensitive region III of the chicken ovalbumin gene is identified, which is located approximately 3.3 kb upstream from the mRNA start site and does not contain palindromic ERE.