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Shu Fen Peng
Researcher at National Tsing Hua University
Publications - 6
Citations - 854
Shu Fen Peng is an academic researcher from National Tsing Hua University. The author has contributed to research in topics: Gene delivery & Receptor-mediated endocytosis. The author has an hindex of 6, co-authored 6 publications receiving 797 citations. Previous affiliations of Shu Fen Peng include China Medical University (Taiwan).
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Journal ArticleDOI
Preparation and characterization of nanoparticles shelled with chitosan for oral insulin delivery.
Yu Hsin Lin,Fwu Long Mi,Chiung-Tong Chen,Wei Chun Chang,Shu Fen Peng,Hsiang Fa Liang,Hsing-Wen Sung +6 more
TL;DR: The in vivo results clearly indicated that the insulin-loaded NPs could effectively reduce the blood glucose level in a diabetic rat model because of their stability in distinct pH environments.
Journal ArticleDOI
The characteristics, cellular uptake and intracellular trafficking of nanoparticles made of hydrophobically-modified chitosan
Ya Ling Chiu,Yi Cheng Ho,Yu-Ming Chen,Shu Fen Peng,Cherng-Jyh Ke,Ko Jie Chen,Fwu Long Mi,Hsing-Wen Sung +7 more
TL;DR: The results obtained in the intracellular trafficking study showed that NPCS NPs entered cells via caveolae and transiently localized to caveosomes before trafficking to the endosomal pathway, suggesting that the prepared NCPS NPs may serve as a carrier for intrACEllular delivery of therapeutic agents.
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The use of biodegradable polymeric nanoparticles in combination with a low-pressure gene gun for transdermal DNA delivery.
Po Wei Lee,Shu Fen Peng,Chun Jen Su,Fwu Long Mi,Hsin-Lung Chen,Ming Cheng Wei,Hao Jan Lin,Hsing-Wen Sung +7 more
TL;DR: Biodegradable nanoparticles, composed of chitosan and poly-gamma-glutamic acid, were prepared by an ionic-gelation method for transdermal DNA delivery using a low-pressure gene gun and revealed that CS/Gamma-PGA/DNA may substitute gold particles as a DNA carrier for transDermal gene delivery.
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A nanoscale drug-entrapment strategy for hydrogel-based systems for the delivery of poorly soluble drugs
Mei Chin Chen,Hung-Wen Tsai,Chin Tang Liu,Shu Fen Peng,Wei Yun Lai,Shiang-Jiuun Chen,Yen Chang,Hsing-Wen Sung +7 more
TL;DR: It was found that the use of a nanoscale drug-entrapment strategy was able to significantly increase the loading efficiency of lipophilic drugs, prevent the drug from aggregation and beneficially reduce its initial burst release; thus, the duration of drug release was extended considerably.
Journal ArticleDOI
The characteristics and in vivo suppression of neointimal formation with sirolimus-eluting polymeric stents.
Mei Chin Chen,Yen Chang,Chin Tang Liu,Wei Yun Lai,Shu Fen Peng,Yi Wen Hung,Hung-Wen Tsai,Hsing-Wen Sung +7 more
TL;DR: It is suggested that the developed sirolimus-eluting polymeric stent, made from chitosan-based strips fixed by an epoxy compound, coated with a hydrophobic heparin, can be a potential alternative for treatment of atherosclerosis.