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Yu Hsin Lin

Researcher at China Medical University (Taiwan)

Publications -  51
Citations -  4474

Yu Hsin Lin is an academic researcher from China Medical University (Taiwan). The author has contributed to research in topics: Cytolethal distending toxin & Cancer cell. The author has an hindex of 29, co-authored 51 publications receiving 3996 citations. Previous affiliations of Yu Hsin Lin include Fu Jen Catholic University & University of Texas Southwestern Medical Center.

Papers
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Journal ArticleDOI

A novel pH-sensitive hydrogel composed of N,O-carboxymethyl chitosan and alginate cross-linked by genipin for protein drug delivery.

Sung Ching Chen, +5 more
- 28 Apr 2004 - 
TL;DR: The results clearly suggested that the genipin-cross-linked NOCC/alginate hydrogel could be a suitable polymeric carrier for site-specific protein drug delivery in the intestine.
Journal ArticleDOI

Physically crosslinked alginate/N,O-carboxymethyl chitosan hydrogels with calcium for oral delivery of protein drugs.

Yu Hsin Lin, +4 more
- 01 May 2005 - 
TL;DR: The calcium-alginate-NOCC beads with distinct total concentrations developed in the study may be used as a potential system for oral delivery of protein drugs to different regions of the intestinal tract.
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Preparation and characterization of nanoparticles shelled with chitosan for oral insulin delivery.

Yu Hsin Lin, +6 more
- 01 Jan 2007 - 
TL;DR: The in vivo results clearly indicated that the insulin-loaded NPs could effectively reduce the blood glucose level in a diabetic rat model because of their stability in distinct pH environments.
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In vivo evaluation of safety and efficacy of self-assembled nanoparticles for oral insulin delivery

Kiran Sonaje, +6 more
- 01 Apr 2009 - 
TL;DR: Oral administration of insulin-loaded NPs demonstrated a significant hypoglycemic action for at least 10h in diabetic rats and the corresponding relative bioavailability of insulin was found to be 15.1+/-0.9%, suggesting that the NPs prepared in the study are a promising vehicle for oral delivery of insulin.
Journal ArticleDOI

Preparation of nanoparticles composed of chitosan/poly-γ-glutamic acid and evaluation of their permeability through Caco-2 cells

Yu Hsin Lin, +5 more
- 22 Jan 2005 - 
TL;DR: Evaluation of the prepared nanoparticles in enhancing intestinal paracellular transport was investigated in vitro and it was found that the nanoparticles with CS dominated on the surfaces could effectively reduce the transepithelial electrical resistance (TEER) of Caco-2 cell monolayers.