S
Sigrid Schmitt
Researcher at University of Giessen
Publications - 22
Citations - 1178
Sigrid Schmitt is an academic researcher from University of Giessen. The author has contributed to research in topics: Glycosylation & Proteome. The author has an hindex of 15, co-authored 22 publications receiving 1101 citations. Previous affiliations of Sigrid Schmitt include University of Göttingen & University of Marburg.
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The Human Dnmt2 Has Residual DNA-(Cytosine-C5) Methyltransferase Activity
TL;DR: It is shown by two independent assay systems that the purified Dnmt2 protein has weak DNA methyltransferase activity, and methylation was observed at CG sites in a loose ttnCGga(g/a) consensus sequence, suggesting that DnMT2 has a more specialized role than other mammalian DNA methyl transferases.
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The biochemical reaction of maize (Zea mays L.) to salt stress is characterized by a mitigation of symptoms and not by a specific adaptation
TL;DR: There appears to be no specific adaptation to salt stress in maize at the level of proteins, and three groups of differentially regulated proteins under low salts stress are detected.
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Proteomic changes in maize roots after short-term adjustment to saline growth conditions
TL;DR: The initial reaction of the proteome and phosphoproteome of maize after adjustment to saline conditions reveals members of sugar signalling and cell signalling pathways such as calmodulin, and gave hint to a transduction chain which is involved in NaCl‐induced signalling.
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Comparative Proteomic Analysis of Lung Tissue from Patients with Idiopathic Pulmonary Fibrosis (IPF) and Lung Transplant Donor Lungs
Martina Korfei,Sigrid Schmitt,Clemens Ruppert,Ingrid Henneke,Philipp Markart,Benjamin Loeh,Poornima Mahavadi,Malgorzata Wygrecka,Walter Klepetko,Ludger Fink,Philippe Bonniaud,Klaus T. Preissner,Günter Lochnit,Liliana Schaefer,Werner Seeger,Andreas Guenther +15 more
TL;DR: Comparative proteome analysis of lung tissue from patients with sporadic IPF and human donor lungs indicates that IPF is characterized by epithelial cell injury, apoptosis, and aberrant epithelial proliferation.
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Fhl-1, a New Key Protein in Pulmonary Hypertension
Grazyna Kwapiszewska,Malgorzata Wygrecka,Leigh M. Marsh,Sigrid Schmitt,Roger Trösser,Jochen Wilhelm,Katja Helmus,B. Eul,Anna Zakrzewicz,Hossein Ardeschir Ghofrani,Ralph T. Schermuly,Rainer M. Bohle,Friedrich Grimminger,Werner Seeger,Oliver Eickelberg,Ludger Fink,Norbert Weissmann +16 more
TL;DR: Protein screening identified Fhl-1 as a novel protein regulated in various forms of PH, including idiopathic pulmonary arterial hypertension, and demonstrated that regulation of FHL-1 was hypoxia-inducible transcription factor dependent.