Andrea Hermann

TL;DR: The current understanding of the molecular enzymology of the mammalian DNA methyltransferases Dnmt1, DNmt3a, DnMT3b and Dn mt2 and the roles of the enzymes in the above-mentioned biological processes are reviewed.

TL;DR: This compendium is intended to provide a basis for the development of a common procedural and terminology framework for the field of human fear conditioning and provides evidence‐based guidance for methodological decisions on study design, outcome measures, and analyses.

TL;DR: It is demonstrated that unmethylated sites embedded in a hemimethylated context are modified at an approximately 24-fold reduced rate, which demonstrates that the enzyme accurately copies existing patterns of methylation.

TL;DR: This study provides first evidence of differential brain activation to visual food stimuli in patients suffering from BED and bulimia nervosa, and displays greater arousal, ACC activation, and insula activation than the other groups.

TL;DR: Dnmt3L acts as a substrate exchange factor that accelerates DNA and AdoMet binding to de novo DNA methyltransferases and induces a conformational change of DnMT3A that opens the active site of the enzyme and promotes binding of DNA and the Ado Met.