S
Silvère Durand
Researcher at Institut Gustave Roussy
Publications - 1
Citations - 397
Silvère Durand is an academic researcher from Institut Gustave Roussy. The author has contributed to research in topics: Autophagy. The author has an hindex of 1, co-authored 1 publications receiving 334 citations.
Papers
More filters
Journal ArticleDOI
Regulation of Autophagy by Cytosolic Acetyl-Coenzyme A
Guillermo Mariño,Federico Pietrocola,Tobias Eisenberg,Yongli Kong,Shoaib Ahmad Malik,Aleksandra Andryushkova,Sabrina Schroeder,Tobias Pendl,Alexandra Harger,Mireia Niso-Santano,Naoufal Zamzami,Marie Scoazec,Silvère Durand,David Enot,Álvaro F. Fernández,Isabelle Martins,Oliver Kepp,Laura Senovilla,Chantal Bauvy,Chantal Bauvy,Eugenia Morselli,Erika Vacchelli,Martin V. Bennetzen,Christoph Magnes,Frank Sinner,Thomas R. Pieber,Carlos López-Otín,Maria Chiara Maiuri,Patrice Codogno,Patrice Codogno,Jens S. Andersen,Joseph A. Hill,Frank Madeo,Guido Kroemer +33 more
TL;DR: It is shown that nutrient starvation causes rapid depletion of AcCoA, and multiple distinct manipulations designed to increase or reduce cytosolic Ac CoA led to the suppression or induction of autophagy, respectively, both in cultured human cells and in mice, delineating Ac coenzyme A-centered pharmacological strategies that allow for the therapeutic manipulation ofautophagy.