Silvia E. Asis

TL;DR: In this article, the multicomponent syntheses of 2,4-di-aryl-quinolines and analogous polycyclic derivatives as anti-tuberculosis agents were described.

TL;DR: Inspired by natural products, indole alkaloids have been used as a nucleus to design new antimalarial drugs as discussed by the authors, which is an infectious disease affecting vulnerable populations in Third World countries.

TL;DR: In this paper, the most promising compound, derived derivative (Ic), was found to have good trypanocidal activities against epimastigotes, trypomastigote, and amstigotes.

TL;DR: Ethyl 2-((4-benzyl-1,4-diazepan-1-yl)methyl)-6-chloro-4-phenylquinoline-3-carboxylate (compound 10) was found to display anti-parasite activity, presenting the highest selectivity index, and the therapeutic effects of compound 10 are promising and suggest a new possibility to treat this disease.