S
Sivakumar Murugadoss
Researcher at Katholieke Universiteit Leuven
Publications - 13
Citations - 555
Sivakumar Murugadoss is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Internal medicine & Engineering. The author has an hindex of 6, co-authored 12 publications receiving 316 citations. Previous affiliations of Sivakumar Murugadoss include Karlsruhe Institute of Technology.
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Journal ArticleDOI
Toxicology of silica nanoparticles: an update.
Sivakumar Murugadoss,Dominique Lison,Lode Godderis,Sybille van den Brule,Jan Mast,Frederic Brassinne,Noham Sebaihi,Peter Hoet +7 more
TL;DR: Despite the multiple studies published in recent years, unambiguous linking of physico-chemical properties of SiNPs types to toxicity, bioavailability, or human health effects is not yet possible.
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Agglomeration of titanium dioxide nanoparticles increases toxicological responses in vitro and in vivo.
Sivakumar Murugadoss,Frederic Brassinne,Noham Sebaihi,J. Pétry,Stevan M. Cokic,Kirsten Van Landuyt,Lode Godderis,Jan Mast,Dominique Lison,Peter Hoet,Sybille van den Brule +10 more
TL;DR: It is observed that large agglomerates of 117 nm TiO 2 induced higher pulmonary responses in aspirated mice and blood DNA damage in gavaged mice compared to small agglomers, and large agg lomerates do not appear less active than small aggLomerates.
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Is aggregated synthetic amorphous silica toxicologically relevant
Sivakumar Murugadoss,Sybille van den Brule,Frederic Brassinne,Noham Sebaihi,Jorge Mejia,Stéphane Lucas,J. Pétry,Lode Godderis,Jan Mast,Dominique Lison,Peter Hoet +10 more
TL;DR: Aggregation resulted in reduced toxicological activity of SAS, and it appeared that aggregates > 100 nm were not necessarily less cytotoxic than their nano-sized counterparts, when comparing aggregates of different sizes.
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Female versus male biological identities of nanoparticles determine the interaction with immune cells in fish
Yuya Hayashi,Yuya Hayashi,Teodora Miclaus,Sivakumar Murugadoss,Masanari Takamiya,Carsten Scavenius,Kasper Kjaer-Sorensen,Jan J. Enghild,Uwe Strähle,Claus Oxvig,Carsten Weiss,Duncan S. Sutherland +11 more
TL;DR: Whether a unique biological identity acquired from sex-specific protein repertoires could alter the degree of nanoparticle uptake by cognate immune cells is examined.
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Air–Liquid Interface Exposure of Lung Epithelial Cells to Low Doses of Nanoparticles to Assess Pulmonary Adverse Effects
Silvia Diabaté,Lucie Armand,Sivakumar Murugadoss,Marco Dilger,Susanne Fritsch-Decker,Christoph Schlager,David Béal,Marie-Edith Arnal,Mathilde Biola-Clier,Selina V. Y. Ambrose,Sonja Mülhopt,Hanns-Rudolf Paur,Iseult Lynch,Eugenia Valsami-Jones,Marie Carrière,Carsten Weiss +15 more
TL;DR: In this paper, human A549 lung epithelial cells and differentiated THP-1 macrophages were exposed under submerged conditions to two abundant types of nanomaterials i.e., ceria and titania nanoparticles (NPs).