Slavko Komarnytsky

TL;DR: The history, future, scientific background and regulatory issues related to botanical therapeutics, including plant-derived pharmaceuticals, multicomponent botanical drugs, dietary supplements, functional foods and plant-produced recombinant proteins are discussed.

TL;DR: Among major polyphenols found in the wild blueberries, malvidin-3-glucoside was significantly more effective than epicatechin or chlorogenic acid in reducing the expression of pro-inflammatory genes in vitro.

TL;DR: The data clearly demonstrate that gut microbiome and the type of the anthocyanin aglycone moiety can alter the protective effect of Anthocyanins against obesity and associated insulin resistance.

TL;DR: Transgenic tobacco is generated that secrete three heterologous proteins of different genetic backgrounds through the leaf intercellular space into tobacco guttation fluid, providing a continuous and nondestructive system for recombinant protein production.

TL;DR: Modulation of protease activity with synthetic peptidomimetic inhibitors has proven to be clinically useful for treating human immunodeficiency virus and hypertension and shows potential for medicinal application in cancer, obesity, cardiovascular, inflammatory, neurodegenerative diseases, and various infectious and parasitic diseases.