S
Sofie Snipstad
Researcher at Norwegian University of Science and Technology
Publications - 34
Citations - 689
Sofie Snipstad is an academic researcher from Norwegian University of Science and Technology. The author has contributed to research in topics: Microbubbles & Drug delivery. The author has an hindex of 12, co-authored 25 publications receiving 418 citations. Previous affiliations of Sofie Snipstad include SINTEF.
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Journal ArticleDOI
Labeling nanoparticles: Dye leakage and altered cellular uptake.
Sofie Snipstad,Sjoerd Hak,Habib Baghirov,Einar Sulheim,Einar Sulheim,Ýrr Mørch,Sylvie Lelu,Eva von Haartman,Marcus Bäck,K. Peter R. Nilsson,Andrey S. Klymchenko,Catharina de Lange Davies,Andreas Åslund +12 more
TL;DR: Surprisingly, incorporation of trace amounts of certain dyes was found to reduce or even inhibit NP uptake and the importance of thoroughly evaluating every dye–NP combination before pursuing NP‐based applications is highlighted.
Journal ArticleDOI
Sonopermeation to improve drug delivery to tumors: from fundamental understanding to clinical translation.
Sofie Snipstad,Sofie Snipstad,Einar Sulheim,Einar Sulheim,Catharina de Lange Davies,Chrit T. W. Moonen,Gert Storm,Gert Storm,Fabian Kiessling,Ruth Schmid,Twan Lammers,Twan Lammers,Twan Lammers +12 more
TL;DR: It is suggested that an improved mechanistic understanding, and microbubbles and ultrasound equipment specialized for drug delivery (and not for imaging) are key aspects to create more effective treatment regimens by sonopermeation.
Journal ArticleDOI
Ultrasound Improves the Delivery and Therapeutic Effect of Nanoparticle-Stabilized Microbubbles in Breast Cancer Xenografts.
Sofie Snipstad,Sigrid Berg,Ýrr Mørch,Astrid Bjørkøy,Einar Sulheim,Rune Hansen,Ingeborg Hovde Grimstad,Annemieke van Wamel,Astri F. Maaland,Sverre H. Torp,Catharina de Lange Davies +10 more
TL;DR: A unique multifunctional drug delivery system consisting of microbubbles stabilized by polymeric nanoparticles (NPMBs), enabling ultrasound-mediated drug delivery is investigated, to determine if increased tumor uptake had a therapeutic benefit.
Journal ArticleDOI
Nanoparticle-stabilized microbubbles for multimodal imaging and drug delivery.
Ýrr Mørch,Rune Hansen,Sigrid Berg,Andreas Åslund,Wilhelm R. Glomm,Wilhelm R. Glomm,Siv Eggen,Ruth Schmid,Heidi Johnsen,Stephan Kubowicz,Sofie Snipstad,Einar Sulheim,Sjoerd Hak,Gurvinder Singh,Birgitte Hjelmeland McDonagh,Hans Blom,Catharina de Lange Davies,Per Stenstad +17 more
TL;DR: It is shown that microbubbles stabilized by polyethylene glycol-coated polymeric nanoparticles can act as contrast agents for conventional ultrasound imaging and could result in increased local deposit of NPs into target tissue, providing improved therapy and imaging contrast compared with freely distributed NPs.
Journal ArticleDOI
Ultrasound-mediated delivery and distribution of polymeric nanoparticles in the normal brain parenchyma of a metastatic brain tumour model.
Habib Baghirov,Sofie Snipstad,Einar Sulheim,Einar Sulheim,Sigrid Berg,Sigrid Berg,Rune Hansen,Rune Hansen,Frits Thorsen,Yrr Mørch,Catharina de Lange Davies,Andreas Åslund +11 more
TL;DR: FUS with nanoparticle-stabilized microbubbles can achieve accumulation and displacement of nanoparticles in the brain parenchyma and the results from acoustic radiation force were not conclusive, but in a few animals some effect could be detected.