S
Solange Costa
Researcher at University of Porto
Publications - 73
Citations - 2489
Solange Costa is an academic researcher from University of Porto. The author has contributed to research in topics: Comet assay & DNA damage. The author has an hindex of 22, co-authored 66 publications receiving 1880 citations. Previous affiliations of Solange Costa include National Institutes of Health & University of Oslo.
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Journal ArticleDOI
Neuronal cytotoxicity and genotoxicity induced by zinc oxide nanoparticles.
Vanessa Valdiglesias,Carla Costa,Gözde Kiliç,Solange Costa,Eduardo Pásaro,Blanca Laffon,João Paulo Teixeira +6 more
TL;DR: The results obtained in this work contribute to increase the knowledge on the genotoxic and cytotoxic potential of ZnO NPs in general, and specifically on human neuronal cells, but further investigations are required to understand the action mechanism underlying the cytot Toxic and Genotoxic effects observed.
Journal ArticleDOI
Variation in the measurement of DNA damage by comet assay measured by the ECVAG inter-laboratory validation trial.
Lykke Forchhammer,Clara Johansson,Steffen Loft,Lennart Möller,Roger W. L. Godschalk,Sabine A. S. Langie,George D. D. Jones,Rachel W. L. Kwok,Andrew Collins,Amaya Azqueta,David H. Phillips,Osman Sozeri,Maciej Stępnik,Jadwiga Palus,Ulla Vogel,Håkan Wallin,Michael N. Routledge,C. Handforth,Alessandra Allione,Giuseppe Matullo,João Paulo Teixeira,Solange Costa,Patrizia Riso,Marisa Porrini,Peter Møller +24 more
TL;DR: In this paper, 12 laboratories analysed the level of DNA damage in monocyte-derived THP-1 cells by either visual classification or computer-aided image analysis of pre-made slides, coded cryopreserved samples of cells and reference standard cells (calibration curve samples).
Journal ArticleDOI
Are iron oxide nanoparticles safe? Current knowledge and future perspectives.
Vanessa Valdiglesias,Natalia Fernández-Bertólez,Gözde Kiliç,Carla Costa,Solange Costa,Sónia Fraga,Maria João Bessa,Eduardo Pásaro,João Paulo Teixeira,Blanca Laffon +9 more
TL;DR: It is shown that influence of nanoparticle surface coating, size, or dose, and of other experimental factors such as treatment time or cell type, has been demonstrated to be important for ION in vitro toxicity manifestation.
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Minimum Information for Reporting on the Comet Assay (MIRCA): recommendations for describing comet assay procedures and results
Peter Møller,Amaya Azqueta,Elisa Boutet-Robinet,Gudrun Koppen,Stefano Bonassi,Mirta Milić,Goran Gajski,Solange Costa,Solange Costa,João Paulo Teixeira,João Paulo Teixeira,Cristiana Pereira,Cristiana Pereira,Maria Dusinska,Roger W. L. Godschalk,Gunnar Brunborg,Kristine B. Gutzkow,Lisa Giovannelli,Marcus S. Cooke,Elke Richling,Blanca Laffon,Vanessa Valdiglesias,Nurşen Başaran,Cristian Del Bo,Bojana Zegura,Matjaz Novak,Helga Stopper,Pavel Vodicka,Pavel Vodicka,Sona Vodenkova,Sona Vodenkova,Vanessa Moraes de Andrade,Monika Sramkova,Alena Gábelová,Andrew Collins,Sabine A. S. Langie,Sabine A. S. Langie +36 more
TL;DR: A Consensus Statement for the Minimum Information for Reporting Comet Assay (MIRCA) providing recommendations for describing comet assay conditions and results and differentiate between ‘desirable’ and ‘essential’ information.
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Integrating health on air quality assessment--review report on health risks of two major European outdoor air pollutants: PM and NO₂.
Solange Costa,Joana Ferreira,Carlos Silveira,Carla Costa,Diogo Lopes,Helder Relvas,Carlos Borrego,Peter Roebeling,Ana Isabel Miranda,João Paulo Teixeira +9 more
TL;DR: An integrated approach combining the effects of several emission abatement measures on air quality, impacts on human health, and associated implementation costs enables an effective cost–benefit analysis and an added value to the decision-making process.