Songhun Jang

TL;DR: It is found that transcriptional activation of the mevalonate pathway and steroid biosynthesis in liver is associated with the grass carp's adaptation from a carnivorous to an herbivorous diet and could serve as an initial platform for breeding better-quality fish using a genomic approach.

TL;DR: Data implied that CiTLR3 is involved in antiviral defense, provide molecular and functional information for grass carp TLR3, and implicate their role in mediating immune protection against grass carp viral diseases.

TL;DR: In the present study, an Mx-like gene was cloned, characterized and gene-transferred in rare minnow Gobiocypris rarus, and its antiviral activity was confirmed in vivo, and it was suggested that introducing more Mx gene improves their resistance to GCRV.

TL;DR: This study effectively separated each gene in the tlr4 gene cluster, implies that grass carp TLR4 proteins have different ligand recognition specificities to mammalian TLRs, and provides information on the functional evolution of TLRs.

TL;DR: Subcellular localization indicated that Ci TLR5a and CiTLR5b shared similar localization pattern and may locate in the plasma membrane of transfected cells and may be involved in response to flagellin stimulation and GCRV infection.