S
Sonia S. Hassan
Researcher at National Institutes of Health
Publications - 12
Citations - 858
Sonia S. Hassan is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Caspase 1 & Inflammasome. The author has an hindex of 11, co-authored 12 publications receiving 550 citations. Previous affiliations of Sonia S. Hassan include Wayne State University.
Papers
More filters
Journal ArticleDOI
Single cell transcriptional signatures of the human placenta in term and preterm parturition.
Roger Pique-Regi,Roger Pique-Regi,Roberto Romero,Adi L. Tarca,Adi L. Tarca,Edward Sendler,Yi Xu,Yi Xu,Valeria Garcia-Flores,Valeria Garcia-Flores,Yaozhu Leng,Yaozhu Leng,Francesca Luca,Sonia S. Hassan,Nardhy Gomez-Lopez,Nardhy Gomez-Lopez +15 more
TL;DR: A catalogue of cell types and transcriptional profiles in the human placenta is provided, shedding light on the molecular underpinnings and non-invasive prediction of the physiologic and pathologic parturition.
Journal ArticleDOI
Vaginal progesterone is as effective as cervical cerclage to prevent preterm birth in women with a singleton gestation, previous spontaneous preterm birth, and a short cervix: updated indirect comparison meta-analysis.
Agustin Conde-Agudelo,Roberto Romero,Eduardo Ribeiro da Fonseca,John M. O'Brien,Elcin Cetingoz,George W. Creasy,Sonia S. Hassan,Offer Erez,Percy Pacora,Kypros H. Nicolaides +9 more
TL;DR: The efficacy of vaginal progesterone has been challenged after publication of the OPPTIMUM study, but this has been resolved by an individual patient‐data meta‐analysis andadjusted indirect comparison meta‐analyses did not show statistically significant differences in the reduction of preterm birth or adverse perinatal outcomes.
Journal ArticleDOI
A Role for the Inflammasome in Spontaneous Labor at Term.
Roberto Romero,Yi Xu,Yi Xu,Olesya Plazyo,Olesya Plazyo,Piya Chaemsaithong,Piya Chaemsaithong,Tinnakorn Chaiworapongsa,Tinnakorn Chaiworapongsa,Ronald Unkel,Ronald Unkel,Nandor Gabor Than,Po Jen Chiang,Zhong Dong,Zhong Dong,Zhonghui Xu,Zhonghui Xu,Adi L. Tarca,Adi L. Tarca,Vikki M. Abrahams,Sonia S. Hassan,Sonia S. Hassan,Lami Yeo,Lami Yeo,Nardhy Gomez-Lopez,Nardhy Gomez-Lopez +25 more
TL;DR: The aims of this study were to determine the expression of major inflammasome components in the chorioamniotic membranes in spontaneous labor at term and whether these events are associated with the release of the mature forms of IL‐1β and IL‐18.
Posted ContentDOI
Single Cell Transcriptional Signatures of the Human Placenta in Term and Preterm Parturition
Roger Pique-Regi,Roger Pique-Regi,Roberto Romero,Adi L. Tarca,Adi L. Tarca,Adi L. Tarca,Edward Sendler,Yi Xu,Yi Xu,Valeria Garcia-Flores,Valeria Garcia-Flores,Yaozhu Leng,Yaozhu Leng,Francesca Luca,Sonia S. Hassan,Sonia S. Hassan,Nardhy Gomez-Lopez,Nardhy Gomez-Lopez +17 more
TL;DR: A catalogue of cell types and transcriptional profiles in the human placenta is provided, shedding light on the molecular underpinnings and non-invasive prediction of the physiologic and pathologic parturition.
Journal ArticleDOI
HMGB1 Induces an Inflammatory Response in the Chorioamniotic Membranes That Is Partially Mediated by the Inflammasome.
Olesya Plazyo,Olesya Plazyo,Roberto Romero,Ronald Unkel,Ronald Unkel,Amapola Balancio,Amapola Balancio,Tara N. Mial,Tara N. Mial,Yi Xu,Yi Xu,Zhong Dong,Zhong Dong,Sonia S. Hassan,Sonia S. Hassan,Nardhy Gomez-Lopez +15 more
TL;DR: Results show that HMGB1 can induce an inflammatory response in the chorioamniotic membranes, which is partially mediated by the inflammasome, and explain why the concentration of this alarmin is increased in women who undergo spontaneous preterm labor.