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Kypros H. Nicolaides
Researcher at University of Cambridge
Publications - 1345
Citations - 96783
Kypros H. Nicolaides is an academic researcher from University of Cambridge. The author has contributed to research in topics: Pregnancy & Trisomy. The author has an hindex of 147, co-authored 1302 publications receiving 87091 citations. Previous affiliations of Kypros H. Nicolaides include University College Hospital & The Chinese University of Hong Kong.
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Journal ArticleDOI
UK multicentre project on assessment of risk of trisomy 21 by maternal age and fetal nuchal-translucency thickness at 10-14 weeks of gestation
TL;DR: Assessment of risk by a combination of maternal age and fetal nuchal-translucency thickness, measured by ultrasonography at 10-14 weeks of gestation, finds that selection of the high-risk group for invasive testing by this method allows the detection of about 80% of affected pregnancies.
Journal ArticleDOI
Aspirin versus Placebo in Pregnancies at High Risk for Preterm Preeclampsia
Daniel L. Rolnik,David Wright,Liona C. Poon,Neil O'Gorman,Argyro Syngelaki,Catalina De Paco Matallana,Ranjit Akolekar,Simona Cicero,D. Janga,Mandeep Singh,Francisca S. Molina,Nicola Persico,Nicola Persico,Jacques Jani,Walter Plasencia,G. Papaioannou,Kinneret Tenenbaum-Gavish,Hamutal Meiri,Sveinbjörn Gizurarson,Kate Maclagan,Kypros H. Nicolaides +20 more
TL;DR: Treatment with low‐dose aspirin in women at high risk for preterm preeclampsia resulted in a lower incidence of this diagnosis than placebo, and there were no significant between‐group differences in the incidence of neonatal adverse outcomes or other adverse events.
Journal ArticleDOI
Fetal nuchal translucency: ultrasound screening for chromosomal defects in first trimester of pregnancy.
TL;DR: Fetal nuchal translucency > or = 3 mm is a useful first trimester marker for fetal chromosomal abnormalities.
Journal ArticleDOI
Clasp - a randomized trial of low-dose aspirin for the prevention and treatment of preeclampsia among 9364 pregnant-women
G Beroyz,R Casale,A Farreiros,M Palermo,M Margulies,L Voto,G Fabregues,R Ramalingam,T Davies,R Bryce,W Boyd,F Carmody,J King,A Vacca,R Fay,W Walters,B Antonas,Phillip R. Bennett,T Broom,C. Crowther,R Derham,K George,William M. Hague,G Hasenhohr,D Heysen,L Kornman,S Oloughlin,D Morris,B Pridmore,J Robinson,D Svigos,R Sweet,M Beale,M Bennett,E Bosch,Chris Fisher,S Horrautz,I Symington,A Szirt,K Forbes,A Freeman,E Popper,Jeffrey R. Wilson,M Permezel,J Bowditch,G Reynolds,R Moulinasse,Y Bietlot,C Kirkpatrick,R Coulon,P Delvoye,C Dematos,S Simonini,B Lejeune,C Neerdaels,Sophie Alexander,L Goessens,M Hanssens,B Spitz,A Vanassche,R Weckhuysen,J Parboosingh,C Harman,Evelyne Rey,R Burrows,J Belcher,P Garner,J Sylvain,C Nimrod,B Thomas,F Deininger,Terence T. Lao,C Li,S Friedman,J Bornstein,A Shalit,A Matzkel,M Pomeranz,M Gelsner,D Mankuta,A Wiznitzer,S Levine,N Adeeb,R Chandran,N Nasri,J Shariff,D Ansell,Y Lake,L Gorochova,V Meriakri,N Romanuga,I Dotz,B Sheuv,E Vikhlyaeva,K Andreev,L Golubeva,V Gorodcov,J Adelantado,J Santonja,H Holmberg,P Buchhave,U Leandersson,J Liljestrand,H Rydhstroem,G Swedin,A Bjorklund,G Gennser,M Sanden,S Dahlgren,S Hammarback,A Smeds,M Sidenvall,E Eneroth,A Szabolcs,I Danielsson,Pelle G. Lindqvist,S Hogstedt,H Wallenburg,Henk A. Bremer,J Briet,A Debiemeyerink,B Donkers,P Lamping,J Schierbeek,L Vanderleeuwharmsen,F Vanbodegom,A Vanegmondlinden,P Flu,J Kuijken,B Morrel,M Straub,M Vierhout,M Keirse,J Vanroosmalen,C Hohner,J Hutten,J Bennen,A Roex,T Wijffels,H Oosterhoff,J Otten,T Vanderklei,J Ramondt,P Vandermoer,J Degraaff,E Sijsma,O Degreve,D Smit,P Smulders,J Nijhuis,H Zondervan,J Lind,B Schoot,M Monkhorst,J Stut,L Vandam,L Vanotterlo,W Vlaanderen,J Eggens,J Santema,A Verhoeff,S Hamid,I John,G Khan,S Shah,E Sheikh,C Sinha,D Abramovich,D Campbell,P Fisher,S Gall,Michael R. Hall,V Jandial,D Parkin,N Smith,H Sutherland,G Swapp,A Templeton,P Terry,A Kalam,S Magee,D Martin,G Spearing,B Alderman,A Murray,J Sutherst,D Hyatt,P Saunders,S Burgess,G Cochrane,A White,M Armstrong,E Mcnichol,G Osbourne,J Price,J Crichton,David M. Evans,Robert Anderson,M Hull,D James,P Niven,G Stirrat,P Wardle,P Gardner,L Padgett,A Alaily,G Nash,B Ginz,Mike U. Smith,C Richards,A Armar,N Armstrong,E Manning,K Persad,M Collingwood,Ronan Collins,J Crowther,Barbara Farrell,B Hafner,H Handoll,J Heineman,S Knight,G Mead,A Radley,S Spence,W Reid,I Treharne,R Heasley,D Lowry,T Myles,R Wallace,M Geals,G Gordon,T Train,D Hutchon,J Macdonald,R Storey,G Anderson,R Worth,J Erian,J Mcqueen,E Tatford,M Terry,R Neale,R Howat,J Kennedy,M Macnaughton,H Mcewan,James J. Walker,R Hutcheson,V Kemp,M Read,M Simms,G Swingler,R Husemeyer,M Chapman,D Maxwell,Murdoch G. Elder,L Fusi,D Hawkins,U Nicolini,R Winston,E Burton,J Fairbank,S Simmons,J Sping,N Trickey,M Gillard,C Hudson,M Setchell,N Wathen,S Canty,P Whiteley,J Campbell,J Feeney,D Hay,A Imrie,A Palmer,D Purdie,E Speck,S. Tyrrell,J Mclean,V Brown,S Duncan,D Johnson,D Millar,D Buckley,M Charnock,P Dove,J Ellis,M Gillmer,J Mcvittie,V Mannion,Christopher W.G. Redman,S Sellers,A Turnbull,M Newman,S Campbell,L Cardoso,D Gibb,K Harrington,J Parsons,Kypros H. Nicolaides,J Studd,R Dixon,C Gie,C Pickles,R Sear,R Graham,P Kirwan,Gregory G. Smith,M Anwar,F Alazzawi,A Davidson,R Dechazel,J Drife,F Gill,G Lang,J Macafee,J Macvicar,N Naftalin,R Neuberg,D Taylor,E Leaver,I Timothy,A Breeson,M Lamb,I Velacott,V Verner,D Horwell,M Lobb,S Seligman,A Scott,S Hall,W.E. Mackenzie,E Smith,S Vethanavagan,J Verzin,P Weir,R White,H Clark,R Fawdry,C Lynch,G Mccune,P Bowensimpkins,J Calvert,S Emery,W Jackson,I Stokes,A Ward,A Browning,C Cox,D Little,H Stibbe,A Mcintosh,C Snodgrass,T Wagstaff,P Howie,J Bibby,W Davies,B Elliott,E Shaxted,J Mcgarry,E Daw,K Baker,A Clubb,J Gough,M Grant,V Menon,M Obhari,P Obrien,Richard J. C. Brown,A Ryall,S Walton,J Baker,J Bruce,D Liu,Ian R. Johnson,A Tyack,D Cowie,A Nysenbaum,P Bamford,D Garrioch,J Hill,Adrian Grant,D Felton,B Hackman,A Falconer,F Freeman,K Greene,J Jackson,G Hunter,D Gratton,T Maulik,H Youssef,G Banwell,R Hartwell,Philippa Wilson,A Bond,P Forbessmith,L Barron,J Davison,W Dunlop,T Lind,D Tacchi,R Balfour,L Mutch,T Coltart,M Deswiet,D K Edmonds,F Loeffler,J Malvern,J Osbourne,Charles H. Rodeck,C Sims,J Spencer,C Bone,A. M. Macdonald,N Drew,R Ballard,R Thonet,L Hanna,S Morcos,E Holt,J Cooper,P Callen,C Fozzard,M Grundy,S Stanley,D Daniel,R Golding,J Wiener,M Buckingham,M Heard,A Letchworth,Kambiz Boomla,A Clark,J Grudzinskas,J Hartgill,D Oram,John Robson,William J. Savage,V Blunt,J Lane,A Owen,D Redford,R Beard,J Bostock,B Measday,H Melville,J Dornan,A Traub,M Utidjian,A Auld,A Kraszewski,D Mack,N Mcdougall,J Mowat,P Docherty,D Mckenna,G Smedley,J Wilde,Richard J.H. Smith,P Watney,J Mcdonnell,P Tromams,Andrew A. Calder,A Glasier,Ian A. Greer,F Johnstone,W. A. Liston,J Livingstone,James P Neilson,S Smith,C West,C Bullough,Anna Bevan Jones,G Mackay,K Cooper,C Ruoss,D Joyce,David McCoy,F Mcleod,P Savage,P Smith,Gill Turner,L Kane,D Rosenberg,R Shannon,D Bromham,P Buchan,A.C. Crompton,G Jarvis,R. J. Lilford,H Macdonald,Jim G Thornton,G Pinker,J Bevan,J Francis,M Kettle,H Holmes,R Kerrwilson,M Sutton,J Beynon,J Hooker,I Fergusson,K Morton,Rennae S. Taylor,Jacky Davis,R Low,J Stewart,F Ashworth,K Soonawalla,I Tebbutt,M Usherwood,J Voigt,Serge Cohen,K Godfrey,G Mcnab,B Murray,D Gudgeon,J Foulkes,P Stannard,R Jamshidi,J Mulholland,E Bond,J Dunlop,P Fogarty,H Brant,L Lachelin,R Lloydjones,N Siddle,A Silverstone,S Steele,R Ward,D Eddie,J Vernonparry,K Cietak,C Kennedy,M Reed,L Santcassia,H Begg,J Frampton,D Griffin,B Lewis,A Nestrop,R Sheridan,R Tipton,S Bober,F Brough,J Stafford,M House,M Pawson,David C. Rees,R Venn,T Anderson,J Hughes,P Reginald,G Henson,H Morgan,I Allen,W Hannay,C Lennox,R Callender,R Mclean,J Goldkrand,C Fidalgo +566 more
TL;DR: The findings do not support routine prophylactic or therapeutic administration of antiplatelet therapy in pregnancy to all women at increased risk of pre-eclampsia or IUGR, but low-dose aspirin may be justified in women judged to be especially liable to early-onset pre- eClampsia severe enough to need very preterm delivery.
Journal ArticleDOI
Progesterone and the risk of preterm birth among women with a short cervix.
TL;DR: In women with a short cervix, treatment with progesterone reduces the rate of spontaneous early preterm delivery and is associated with a nonsignificant reduction in neonatal morbidity.