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Stefan Nessler
Researcher at University of Göttingen
Publications - 53
Citations - 3906
Stefan Nessler is an academic researcher from University of Göttingen. The author has contributed to research in topics: Experimental autoimmune encephalomyelitis & Multiple sclerosis. The author has an hindex of 24, co-authored 53 publications receiving 3242 citations. Previous affiliations of Stefan Nessler include Technische Universität München & University of Düsseldorf.
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Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution.
Takahiro Masuda,Roman Sankowski,Ori Staszewski,Chotima Böttcher,Lukas Amann,Sagar,Christian Scheiwe,Stefan Nessler,Patrik Kunz,Geert van Loo,Volker A. Coenen,Peter C. Reinacher,Anna Michel,Ulrich Sure,Ralf Gold,Dominic Grün,Josef Priller,Josef Priller,Christine Stadelmann,Marco Prinz +19 more
TL;DR: Insight is provided into the endogenous immune system of the central nervous system during development, homeostasis and disease, and may also provide new targets for the treatment of neurodegenerative and neuroinflammatory pathologies.
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Intrathecal pathogenic anti–aquaporin‐4 antibodies in early neuromyelitis optica
Jeffrey Bennett,Chiwah Lam,Sudhakar Reddy Kalluri,Philippe Saikali,Katherine Bautista,Cecily Dupree,Magdalena J. Glogowska,David Case,Jack P. Antel,Gregory P. Owens,Donald H. Gilden,Stefan Nessler,Christine Stadelmann,Bernhard Hemmer +13 more
TL;DR: The serum of most neuromyelitis optica patients contains autoantibodies directed against the aquaporin‐4 water channel located on astrocyte foot processes in the perivessel and subpial areas of the brain, and their role in disease pathogenesis was determined.
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Acute disseminated encephalomyelitis: an update.
Til Menge,Bernhard Hemmer,Stefan Nessler,Heinz Wiendl,Oliver Neuhaus,Hans-Peter Hartung,Bernd C. Kieseier,Olaf Stüve +7 more
TL;DR: A number of recently conducted observational case series have substantially broadened the understanding about the clinical phenotype, diagnosis, and prognosis of acute disseminated encephalomyelitis.
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Identification of Epstein-Barr virus proteins as putative targets of the immune response in multiple sclerosis
Sabine Cepok,Dun Zhou,Rajneesh Srivastava,Stefan Nessler,Susanne Stei,Konrad Büssow,Norbert Sommer,Bernhard Hemmer +7 more
TL;DR: Findings demonstrate an increased immune response to EBV in MS patients, which suggests that the virus plays an important role in the pathogenesis of disease.
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Immunopathogenesis and immunotherapy of multiple sclerosis.
TL;DR: Current knowledge of the immunopathogenesis of MS and corresponding animal models of disease is reviewed, new immunointerventional treatment strategies based on changing pathogenetic concepts are discussed, and new immunotherapeutic agents developed and evaluated in clinical trials are discussed.