S
Stefania Mitola
Researcher at University of Brescia
Publications - 117
Citations - 5606
Stefania Mitola is an academic researcher from University of Brescia. The author has contributed to research in topics: Angiogenesis & Endothelial stem cell. The author has an hindex of 34, co-authored 107 publications receiving 5085 citations. Previous affiliations of Stefania Mitola include University of Turin.
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Journal ArticleDOI
Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis.
TL;DR: This review will focus on the relevance of the FGF/FGF receptor system in adult angiogenesis and its contribution to tumor vascularization.
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Role of αvβ3 integrin in the activation of vascular endothelial growth factor receptor‐2
Raffaella Soldi,Stefania Mitola,Marina Strasly,Paola Defilippi,Guido Tarone,Federico Bussolino +5 more
TL;DR: A new role for αvβ3 integrin is indicated in the activation of an in vitro angiogenic program in endothelial cells by participating in the full activation of VEGFR‐2 triggered by VEGF‐A, which is an importantAngiogenic inducer in tumors, inflammation and tissue regeneration.
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Cutting Edge: Extracellular High Mobility Group Box-1 Protein Is a Proangiogenic Cytokine
Stefania Mitola,Mirella Belleri,Chiara Urbinati,Daniela Coltrini,Bianca Sparatore,Marco Pedrazzi,Edon Melloni,Marco Presta +7 more
TL;DR: HMGB1 exerts proangiogenic effects by inducing MAPK ERK1/2 activation, cell proliferation, and chemotaxis in endothelial cells of different origin by inhibits HMGB1-induced neovascularization in vivo and endothelial cell proliferation and membrane ruffling in vitro.
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Gremlin is a novel agonist of the major proangiogenic receptor VEGFR2
Stefania Mitola,Cosetta Ravelli,Emanuela Moroni,Valentina Salvi,Daria Leali,Kurt Ballmer-Hofer,Luca Zammataro,Marco Presta +7 more
TL;DR: Gremlin represents a novel proangiogenic VEGFR2 agonist distinct from the VEGF family ligands with implications in vascular development, angiogenesis-dependent diseases, and tumor neovascularization.
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IL-12 inhibition of endothelial cell functions and angiogenesis depends on lymphocyte-endothelial cell cross-talk.
Marina Strasly,Federica Cavallo,Massimo Geuna,Stefania Mitola,Mario P. Colombo,Guido Forni,Federico Bussolino +6 more
TL;DR: It is shown that IL-12 activates an anti-angiogenic program in Con A-activated mouse spleen cells (activated spc) or human PBMC (activated PBMC) and that the IFN-inducible protein-10 and monokine-induced by IFn-γ chemokines are pivotal in inducing these effects.