S
Stefanie Kuerten
Researcher at University of Erlangen-Nuremberg
Publications - 57
Citations - 1055
Stefanie Kuerten is an academic researcher from University of Erlangen-Nuremberg. The author has contributed to research in topics: Experimental autoimmune encephalomyelitis & Multiple sclerosis. The author has an hindex of 16, co-authored 57 publications receiving 783 citations. Previous affiliations of Stefanie Kuerten include University of Würzburg.
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Journal ArticleDOI
Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells
Kerstin Göbel,Susann Pankratz,Chloi-Magdalini Asaridou,Alexander M. Herrmann,Stefan Bittner,Stefan Bittner,Monika Merker,Tobias Ruck,Sarah Glumm,Friederike Langhauser,Peter Kraft,Thorsten F. Krug,Johanna Breuer,Martin Herold,Catharina C. Gross,Denise Beckmann,Adelheid Korb-Pap,Michael K. Schuhmann,Stefanie Kuerten,Ioannis Mitroulis,Clemens Ruppert,Marc W. Nolte,Con Panousis,Luisa Klotz,Beate E. Kehrel,Thomas Korn,Harald F. Langer,Thomas Pap,Bernhard Nieswandt,Heinz Wiendl,Triantafyllos Chavakis,Christoph Kleinschnitz,Sven G. Meuth +32 more
TL;DR: It is demonstrated that a member of the plasmatic coagulation cascade is a key mediator of autoimmunity and FXII inhibition may provide a strategy to combat MS and other immune-related disorders.
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Emerging concepts in autoimmune encephalomyelitis beyond the CD4/T(H)1 paradigm.
TL;DR: Data is reviewed on how a complex network of immune mechanisms is involved in the pathogenesis of MS and EAE and the traditional CD4/T(H)1 paradigm is critically reevaluate.
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The immune pathogenesis of experimental autoimmune encephalomyelitis: lessons learned for multiple sclerosis?
Stefanie Kuerten,Paul V. Lehmann +1 more
TL;DR: An overview of the current understanding of the discrete steps that lead to the pathogenesis of EAE is provided, and several junctions at which the perpetuation or abortive course of the disease is defined are highlighted.
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Nimodipine fosters remyelination in a mouse model of multiple sclerosis and induces microglia-specific apoptosis.
Andrea Schampel,Oleg Volovitch,Tobias Koeniger,Claus Jürgen Scholz,Stefanie Jörg,Ralf A. Linker,Erhard Wischmeyer,Marie Wunsch,Johannes W. Hell,Süleyman Ergün,Stefanie Kuerten +10 more
TL;DR: Nimodipine application seems to generate a favorable environment for regenerative processes and therefore could be a treatment option for MS, because it combines features of immunomodulation with beneficial effects on neuroregeneration.
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The vascular adventitia: An endogenous, omnipresent source of stem cells in the body.
Philipp Wörsdörfer,Subba Rao Mekala,Jochen Bauer,Frank Edenhofer,Stefanie Kuerten,Süleyman Ergün +5 more
TL;DR: An overview about the current knowledge on VW-SCs is provided and strategies how these adult stem cells could be manipulated in order to activate and expand them, ideally within their niche at sites of tissue damage and subsequently differentiate them into a desired cell type, e.g. an endothelial cell, a macrophage or a muscle cell are discussed.