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Stephanie Glavaris
Researcher at Johns Hopkins University School of Medicine
Publications - 27
Citations - 799
Stephanie Glavaris is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Prostate cancer & Circulating tumor cell. The author has an hindex of 12, co-authored 23 publications receiving 575 citations. Previous affiliations of Stephanie Glavaris include Johns Hopkins University.
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Journal ArticleDOI
Tissue-based Genomics Augments Post-prostatectomy Risk Stratification in a Natural History Cohort of Intermediate- and High-Risk Men
Ashley E. Ross,Michael H. Johnson,Kasra Yousefi,Elai Davicioni,George J. Netto,Luigi Marchionni,Helen L. Fedor,Stephanie Glavaris,Voleak Choeurng,Christine Buerki,Nicholas Erho,Lucia L. Lam,Elizabeth B. Humphreys,Sheila F. Faraj,Stephania M. Bezerra,Misop Han,Alan W. Partin,Bruce J. Trock,Edward M. Schaeffer +18 more
TL;DR: In a patient population that received no adjuvant or salvage therapy after prostatectomy until metastatic progression, higher Decipher scores correlated with clinical events, and inclusion ofdecipher scores improved the prognostic performance of validated clinicopathologic risk models confirm the utility already reported for Decipher.
Journal ArticleDOI
MSH2 Loss in Primary Prostate Cancer.
Liana B. Guedes,Emmanuel S. Antonarakis,Michael T. Schweizer,Nooshin Mirkheshti,Fawaz Almutairi,Jong Chul Park,Stephanie Glavaris,Jessica L. Hicks,Mario A. Eisenberger,Angelo M. De Marzo,Jonathan I. Epstein,William B. Isaacs,James R. Eshleman,Colin C. Pritchard,Tamara L. Lotan +14 more
TL;DR: Loss of MSH 2 protein is correlated with MSH2 inactivation, hypermutation, and higher tumor-infiltrating lymphocyte density, and appears most common among very high-grade primary tumors, for which routine screening may be warranted if validated in additional cohorts.
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Correlation of B7-H3 with androgen receptor, immune pathways and poor outcome in prostate cancer: An expression-based analysis
Benjamin Benzon,Shuang G. Zhao,Michael C. Haffner,M. Takhar,Nicholas Erho,Kasra Yousefi,Paula J. Hurley,Jennifer L. Bishop,Jeffrey J. Tosoian,Kamyar Ghabili,Mohammed Alshalalfa,Stephanie Glavaris,Brian W. Simons,Phuoc T. Tran,E Davicioni,Robert Jeffrey Karnes,K Boudadi,K Boudadi,Emmanuel S. Antonarakis,Edward M. Schaeffer,Charles G. Drake,F Feng,Ashley E. Ross +22 more
TL;DR: Higher B7-H3 expression correlates with Gleason grade, prostate cancer stage and poor oncologic outcomes in prostatectomy cohorts, andGene set enrichment analysis demonstrated an association of B7,H3 with androgen signaling as well as immune regulatory pathways.
Journal ArticleDOI
Prevalence and Prognostic Significance of PTEN Loss in African-American and European-American Men Undergoing Radical Prostatectomy
Jeffrey J. Tosoian,Fawaz Almutairi,Carlos L. Morais,Stephanie Glavaris,Jessica Hicks,Debasish Sundi,Debasish Sundi,Elizabeth B. Humphreys,Misop Han,Angelo M. De Marzo,Ashley E. Ross,Scott A. Tomlins,Edward M. Schaeffer,Edward M. Schaeffer,Bruce J. Trock,Tamara L. Lotan +15 more
TL;DR: PTEN and ERG alterations in prostate cancer are less likely in African-American than in European-American men, however, PTEN loss remains associated with poor prostate cancer outcomes among African- American men.
Journal ArticleDOI
Genome-wide association and multi-omic analyses reveal ACTN2 as a gene linked to heart failure.
Marios Arvanitis,Emmanouil Tampakakis,Yanxiao Zhang,Wei Wang,Adam Auton,Diptavo Dutta,Stephanie Glavaris,Ali R. Keramati,Nilanjan Chatterjee,Neil C. Chi,Bing Ren,Bing Ren,Wendy S. Post,Alexis Battle +13 more
TL;DR: A large scale meta-analysis of heart failure GWAS and replication in a comparable sized cohort to identify one known and two novel loci associated with heart failure reveal a putative causal variant in a cardiac muscle specific regulatory region activated during cardiomyocyte differentiation that binds to the ACTN2 gene.