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Luigi Marchionni

Researcher at Cornell University

Publications -  181
Citations -  12273

Luigi Marchionni is an academic researcher from Cornell University. The author has contributed to research in topics: Prostate cancer & Cancer. The author has an hindex of 44, co-authored 155 publications receiving 10862 citations. Previous affiliations of Luigi Marchionni include Johns Hopkins University & Harvard University.

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The Transcriptional Landscape of the Mammalian Genome

Piero Carninci, +197 more
- 02 Sep 2005 - 
TL;DR: Detailed polling of transcription start and termination sites and analysis of previously unidentified full-length complementary DNAs derived from the mouse genome provide a comprehensive platform for the comparative analysis of mammalian transcriptional regulation in differentiation and development.
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Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs

Yasushi Okazaki, +138 more
- 05 Dec 2002 - 
TL;DR: The present work, completely supported by physical clones, provides the most comprehensive survey of a mammalian transcriptome so far, and is a valuable resource for functional genomics.
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Functional annotation of a full-length mouse cDNA collection

Jun Kawai, +96 more
- 08 Feb 2001 - 
TL;DR: The first RIKEN clone collection is described, which is one of the largest described for any organism and analysis of these cDNAs extends known gene families and identifies new ones.
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A Primary Xenograft Model of Small-Cell Lung Cancer Reveals Irreversible Changes in Gene Expression Imposed by Culture In vitro

TL;DR: A primary xenograft model of small-cell lung cancer is described in which endobronchial tumor specimens obtained from chemo-naive patients are serially propagated in vivo in immunodeficient mice to identify a group of tumor-specific genes expressed in primary SCLC and Xenografts that was lost during the transition to tissue culture and that was not regained when the tumors were reestablished as secondary xenografteds.
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Only three driver gene mutations are required for the development of lung and colorectal cancers

TL;DR: It is shown that only three sequential mutations are required to develop lung and colon adenocarcinomas, a number that is lower than what is typically thought to be required for the formation of cancers of these and other organs.