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Stephen R. Master

Researcher at Children's Hospital of Philadelphia

Publications -  89
Citations -  4042

Stephen R. Master is an academic researcher from Children's Hospital of Philadelphia. The author has contributed to research in topics: Medicine & DNA methylation. The author has an hindex of 31, co-authored 81 publications receiving 3677 citations. Previous affiliations of Stephen R. Master include Hospital of the University of Pennsylvania & Cornell University.

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Mutations in either the essential or regulatory light chains of myosin are associated with a rare myopathy in human heart and skeletal muscle

TL;DR: It is suggested that the mutations associated with the identification of distinct missense mutations in a skeletal/ventricular ELC and RLC are associated with a rare variant of cardiac hypertrophy as well as abnormal skeletal muscle.
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The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor

TL;DR: The results establish Pim-2 as a direct link between growth factor-induced transcription and a novel, kinase-dependent pathway that promotes cell-autonomous survival.
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Fibroblast growth factor 23 is not associated with and does not induce arterial calcification

TL;DR: Whereas elevated phosphate concentrations induced calcification in vitro, FGF23 had no effect on phosphate uptake or phosphate-induced calcification regardless of phosphate concentration or even in the presence of soluble klotho, thus, in contrast to serum phosphate, F GF23 is not associated with arterial calcification and does not promote calcification experimentally.
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Differential Expression of miRNAs in Papillary Thyroid Carcinoma Compared to Multinodular Goiter Using Formalin Fixed Paraffin Embedded Tissues

TL;DR: This work exploited the ability to procure sufficient miRNA from formalin-fixed paraffin-embedded (FFPE) tissue to describe a series of miRNAs whose expression is dysregulated in PTC compared to benign proliferative multinodular goiter (MNG), and suggested that FFPE tissues are suitable resources for miRNA expression analyses.
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Vision Diagnoses Are Common After Concussion in Adolescents

TL;DR: A high prevalence of vision diagnoses (accommodative, binocular convergence, and saccadic eye movement disorders) was found in this sample of adolescents with concussion, with some manifesting more than one vision diagnosis.