R
Radhakrishna R. Kallem
Researcher at University of Pennsylvania
Publications - 29
Citations - 1665
Radhakrishna R. Kallem is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Kidney disease & Renal function. The author has an hindex of 18, co-authored 28 publications receiving 1308 citations. Previous affiliations of Radhakrishna R. Kallem include Case Western Reserve University.
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Journal ArticleDOI
Fibroblast growth factor 23 is not associated with and does not induce arterial calcification
Julia J. Scialla,Wei Ling Lau,Muredach P. Reilly,Tamara Isakova,Hsueh Ying Yang,Matthew H. Crouthamel,Nicholas W. Chavkin,Mahboob Rahman,Patricia Wahl,Ansel P. Amaral,Takayuki Hamano,Stephen R. Master,Lisa Nessel,Boyang Chai,Dawei Xie,Radhakrishna R. Kallem,Jing Chen,James P. Lash,John W. Kusek,Matthew J. Budoff,Cecilia M. Giachelli,Myles Wolf +21 more
TL;DR: Whereas elevated phosphate concentrations induced calcification in vitro, FGF23 had no effect on phosphate uptake or phosphate-induced calcification regardless of phosphate concentration or even in the presence of soluble klotho, thus, in contrast to serum phosphate, F GF23 is not associated with arterial calcification and does not promote calcification experimentally.
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Blood Pressure and Risk of All-Cause Mortality in Advanced Chronic Kidney Disease and Hemodialysis The Chronic Renal Insufficiency Cohort Study
Nisha Bansal,Charles E. McCulloch,Mahboob Rahman,John W. Kusek,Amanda H. Anderson,Dawei Xie,Raymond R. Townsend,Claudia M. Lora,Jackson T. Wright,Alan S. Go,Akinlolu O. Ojo,Arnold B. Alper,Eva Lustigova,Magda Cuevas,Radhakrishna R. Kallem,Chi-yuan Hsu +15 more
TL;DR: In this paper, the association between systolic blood pressure (SBP) and mortality in advanced chronic kidney disease and after initiation of hemodialysis was evaluated in chronic renal insufficiency patients.
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Predictors of high sensitivity cardiac troponin T in chronic kidney disease patients: a cross-sectional study in the chronic renal insufficiency cohort (CRIC)
Ruth F. Dubin,Yongmei Li,Jiang He,Bernard G. Jaar,Radhakrishna R. Kallem,James P. Lash,Gail Makos,Sylvia E. Rosas,Elsayed Z. Soliman,Raymond R. Townsend,Wei Yang,Alan S. Go,Martin G. Keane,Christopher DeFilippi,Rakesh Mishra,Myles Wolf,Michael G. Shlipak +16 more
TL;DR: Knowledge of the determinants of hs-TnT in this cohort may guide further research on the pathology of heart disease in patients with CKD and help to stratify sub-groups of CKD patients at higher cardiovascular risk.
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Plant Protein Intake is Associated With Fibroblast Growth Factor 23 and Serum Bicarbonate Levels in Patients With Chronic Kidney Disease: The Chronic Renal Insufficiency Cohort Study
Julia J. Scialla,Lawrence J. Appel,Myles Wolf,Wei Yang,Xiaoming Zhang,Stephen M. Sozio,Edgar R. Miller,Lydia A. Bazzano,Magdalena Cuevas,Melanie Glenn,Eva Lustigova,Radhakrishna R. Kallem,Anna C. Porter,Raymond R. Townsend,Matthew R. Weir,Cheryl A.M. Anderson +15 more
TL;DR: Consumption of a higher percentage of protein from plant sources may lower FGF-23 and raise HCO₃ levels in patients with CKD.
Journal ArticleDOI
Arterial Stiffness, Central Pressures, and Incident Hospitalized Heart Failure in the Chronic Renal Insufficiency Cohort Study
Julio A. Chirinos,Abigail Khan,Nisha Bansal,Daniel L. Dries,Harold I. Feldman,Virginia Ford,Amanda H. Anderson,Radhakrishna R. Kallem,James P. Lash,Akinlolu O. Ojo,Martin J. Schreiber,Angela Sheridan,Jillian Strelsin,Valerie Teal,Jason Roy,Qiang Pan,Alan S. Go,Raymond R. Townsend +17 more
TL;DR: Large artery stiffness is an independent predictor of incident HF in chronic kidney disease, an association with strong biological plausibility given the known effects of large artery stiffening of left ventricular pulsatile load.