S
Steven Haugbøl
Researcher at Copenhagen University Hospital
Publications - 24
Citations - 1304
Steven Haugbøl is an academic researcher from Copenhagen University Hospital. The author has contributed to research in topics: Altanserin & Kindling. The author has an hindex of 15, co-authored 24 publications receiving 1216 citations.
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Journal ArticleDOI
MR-based automatic delineation of volumes of interest in human brain PET images using probability maps
Claus Svarer,Karine Madsen,Steen G. Hasselbalch,Lars H. Pinborg,Steven Haugbøl,Vibe G. Frokjaer,Søren Holm,Olaf B. Paulson,Gitte M. Knudsen +8 more
TL;DR: In this article, an observer-independent approach for automatic generation of volume-of-interest (VOI) brain templates to be used in emission tomography studies of the brain was developed and validated.
Journal ArticleDOI
Frontolimbic serotonin 2A receptor binding in healthy subjects is associated with personality risk factors for affective disorder
Vibe G. Frokjaer,Erik Lykke Mortensen,Finn Årup Nielsen,Finn Årup Nielsen,Steven Haugbøl,Lars H. Pinborg,Karen H. Adams,Claus Svarer,Steen G. Hasselbalch,S. Holm,Olaf B. Paulson,Gitte M. Knudsen +11 more
TL;DR: The findings point to a neurobiological link between personality risk factors for affective disorder and the serotonergic transmitter system and identify the serotonin 2A receptor as a biomarker for vulnerability to affective disorders.
Journal ArticleDOI
A database of [(18)F]-altanserin binding to 5-HT(2A) receptors in normal volunteers: normative data and relationship to physiological and demographic variables.
Karen H. Adams,Lars H. Pinborg,Claus Svarer,Steen G. Hasselbalch,Søren Holm,Steven Haugbøl,Karine Madsen,Vibe G. Frokjaer,Lars Martiny,Olaf B. Paulson,Gitte M. Knudsen +10 more
TL;DR: The regional distribution of [(18)F]-altanserin binding in the healthy human brain was in agreement with existing in vitro post-mortem human 5-HT(2A) data, and cerebellar binding appears to be unaffected by gender, but the effects of ageing must be considered for clinical studies.
Journal ArticleDOI
Quantification of 5-HT2A receptors in the human brain using [18F]altanserin-PET and the bolus/infusion approach.
Lars H. Pinborg,Karen H. Adams,Claus Svarer,Søren Holm,Steen G. Hasselbalch,Steven Haugbøl,Jacob Madsen,Gitte M. Knudsen +7 more
TL;DR: It is concluded that 5-HT2A receptor studies can be conducted within 2 h of [18F]altanserin infusion, yielding reliable results.
Journal ArticleDOI
Brain serotonin 2A receptor binding: relations to body mass index, tobacco and alcohol use.
David Erritzoe,Vibe G. Frokjaer,Steven Haugbøl,Lisbeth Marner,Claus Svarer,Klaus K. Holst,William F. C. Baaré,Peter Mondrup Rasmussen,Jacob Madsen,Olaf B. Paulson,Gitte M. Knudsen +10 more
TL;DR: It is suggested that the observation is driven by a lower central 5-HT level in overweight people, leading both to increased food intake and to a compensatory upregulation of cerebral 5- HT(2A) receptor density.