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Suet Yi Leung
Researcher at University of Hong Kong
Publications - 252
Citations - 34944
Suet Yi Leung is an academic researcher from University of Hong Kong. The author has contributed to research in topics: Cancer & Gene. The author has an hindex of 68, co-authored 239 publications receiving 32462 citations. Previous affiliations of Suet Yi Leung include University of Missouri & Queen Mary University of London.
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Journal ArticleDOI
Association of Inflammation-Related and microRNA Gene Expression with Cancer-Specific Mortality of Colon Adenocarcinoma
Aaron J. Schetter,Giang Nguyen,Elise D. Bowman,Ewy Mathé,Siu Tsan Yuen,Jason E. Hawkes,Carlo M. Croce,Suet Yi Leung,Curtis C. Harris +8 more
TL;DR: Both IRS and miR-21 expression were independently associated with cancer-specific mortality, including stage II patients alone, and may provide a clinically useful tool to identify high-risk patients.
Journal ArticleDOI
Monocyte chemoattractant protein-1 expression and macrophage infiltration in gliomas
TL;DR: It is proposed that the mechanism of macrophage recruitment is, at least partly, effected by constitutive expression and T cell-mediated up-regulation of MCP-1 in tumour cells and TAM, which establishes a positive amplification circuit for macrophages recruitment in gliomas.
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Expression of Vascular Endothelial Growth Factor and Its Receptors in the Anaplastic Progression of Astrocytoma, Oligodendroglioma, and Ependymoma
Annie S Y Chan,Suet Yi Leung,Maria Pik Wong,Siu Tsan Yuen,N Cheung,Yiu Wah Fan,Lap Ping Chung +6 more
TL;DR: Results showed that VEGF was moderately to strongly expressed in 8 of 10 ependymomas and in all anaplastic oligodendrogliomas and glioblastoma multiforme cases, and the findings from the in situ hybridization study correlated with the expression index, as determined by reverse transcription polymerase chain reaction.
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Mutations of PIK3CA in gastric adenocarcinoma.
Vivian S. W. Li,Chi Wai Wong,Tsun Leung Chan,Agnes Chan,Wei Zhao,Kent-Man Chu,Samuel So,Xin Chen,Siu Tsan Yuen,Suet Yi Leung +9 more
TL;DR: The data suggested that activation of the PI3K signalling pathway in gastric cancer may be achieved through up-regulation or mutation of PIK3CA, in which the latter may be a consequence of mismatch repair deficiency.
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Phospholipase A2 group IIA expression in gastric adenocarcinoma is associated with prolonged survival and less frequent metastasis
Suet Yi Leung,Xin Chen,Kent Man Chu,Siu Tsan Yuen,Jonathan A. Mathy,Jiafu Ji,Annie S Y Chan,Rui Li,Simon Law,Olga G. Troyanskaya,I-Ping Tu,John Wong,Samuel So,David Botstein,Patrick O. Brown +14 more
TL;DR: Exposure of PLA2G2A, a gene previously implicated as a modifier of the ApcMin/+ (multiple intestinal neoplasia 1) mutant phenotype in the mouse, was significantly correlated with patient survival, suggesting the intriguing possibility that the activity ofPLA2G1A may suppress progression or metastasis of human gastric cancer.