Suet Yi Leung

TL;DR: In this article , a statistical approach was developed to identify patients with GCV-associated mutational signature (GCV sig ) from targeted sequenced data of tumour samples, and cell line exposure models were further used to quantify mutation burden and DNA damage caused by GCV and other antiviral and immunosuppressive drugs.

TL;DR: In this article, the electron energy bands for graphite intercalation compounds are calculated using a model based on the well-established electronic structure of pristine graphite, which is applicable to any intercalant and stage, and predicts stage dependent Shubnikov-de Haas and optical spectra.

TL;DR: 39% of young CRCs in Guangzhou showed no evidence of either chromosomal instability or microsatellite instability carcinogentic pathway, indicating that there must be at least a third pathway which triggers the CRC's in these special subgroups of young patients in Guang Shanghai.

TL;DR: It was shown that chemotherapy benefit was different in the 3 GC clusters and varied depending on the tumor stage, suggesting significance of the methylation-driven key regulators in molecular and histological heterogeneity of GC.