Sung Ho Park

TL;DR: It is proposed that the type I IFN response plays a pivotal role in exacerbating inflammation in severe COVID-19.

TL;DR: It is shown that tumor-infiltrating T cells are severely exhausted in the microsatellite stable (MSS) colorectal cancer (CRC), a representative example of PD-1 blockade–resistant tumors, and VEGF-A induces the expression of transcription factor TOX in T cells to drive exhaustion-specific transcription program in T Cells.

TL;DR: Results elucidate fundamental aspects of the immune response dynamics provoked by SARS-CoV-2 infection and find that different spectrums of M1 or M2 macrophages showed distinct patterns of gene modules downregulated by immune-modulatory drugs.

TL;DR: Findings show that PM2.5 can promote the ROS/p38 MAPK/NF-κB signaling pathway and lead to mitochondrial damage and DNA double-strand break, which is ultimately caused inflammation and cytotoxicity in RCECs.

TL;DR: Taken together, Cav1.2 maybe considered to be a therapeutic candidate to decrease the collective migration and invasion of Ameloblastoma.