Su-Hyung Park

TL;DR: It is proposed that the type I IFN response plays a pivotal role in exacerbating inflammation in severe COVID-19.

TL;DR: It is suggested that prolonged innate immune activation by HCV impairs the development of successful adaptive immune responses, and comparative immunology provides insights into the maintenance of immune protection.

TL;DR: The similarities and differences in immune responses to and immunopathogenesis of HAV, HBV and HCV infections are discussed, which may explain the distinct courses and outcomes of each hepatitis virus infection.

TL;DR: HCC specimens are found to contain CD8+ T cells that express different levels of PD1, or an impaired capacity to secrete cytokines and proliferate with overexpression of immune checkpoint receptors, which occurs during chronic viral infections but has also been observed in tumors.

TL;DR: Clinical characteristics, cytokine/chemokine concentrations, viral shedding and antibody kinetics in 30 patients with Middle East respiratory syndrome (MERS), including 6 non-survivors admitted to 3 MERS-designated hospitals, found old age, low albumin, altered mentality and high pneumonia severity index score at admission were risk factors for mortality.