M
Moa Sa
Researcher at KAIST
Publications - 7
Citations - 962
Moa Sa is an academic researcher from KAIST. The author has contributed to research in topics: CD8 & Memory T cell. The author has an hindex of 4, co-authored 7 publications receiving 460 citations.
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Journal ArticleDOI
Immunophenotyping of COVID-19 and influenza highlights the role of type I interferons in development of severe COVID-19.
Jeong Seok Lee,Seongwan Park,Hye Won Jeong,Jin Young Ahn,Seong Jin Choi,Ho-Young Lee,Baekgyu Choi,Su Kyung Nam,Moa Sa,Ji Soo Kwon,Ji Soo Kwon,Su Jin Jeong,Heung Kyu Lee,Sung Ho Park,Su-Hyung Park,Jun Yong Choi,Sung-Han Kim,Inkyung Jung,Eui-Cheol Shin +18 more
TL;DR: It is proposed that the type I IFN response plays a pivotal role in exacerbating inflammation in severe COVID-19.
Journal ArticleDOI
PD-1-Expressing SARS-CoV-2-Specific CD8 + T Cells Are Not Exhausted, but Functional in Patients with COVID-19.
Min-Seok Rha,Hye Won Jeong,Jae-Hoon Ko,Seongjin Choi,In Ho Seo,Jeong Seok Lee,Moa Sa,A. Reum Kim,Eun Jeong Joo,Jin Young Ahn,Jung Ho Kim,Kyoung Ho Song,Eu Suk Kim,Dong Hyun Oh,Mi Young Ahn,Hee Kyoung Choi,Ji Hoon Jeon,Jae-Phil Choi,Hong Bin Kim,Young Keun Kim,Su-Hyung Park,Won Suk Choi,Jun Yong Choi,Kyong Ran Peck,Eui-Cheol Shin +24 more
TL;DR: Cytokine secretion assays combined with MHC class I multimer staining revealed that the proportion of interferon-γ (IFN-γ)-producing cells was significantly lower among SARS-CoV-2-specific CD8+ T cells than those specific to influenza A virus.
Journal ArticleDOI
SARS-CoV-2-specific T cell memory is sustained in COVID-19 convalescent patients for 10 months with successful development of stem cell-like memory T cells.
Jae Hyung Jung,Min-Seok Rha,Min-Seok Rha,Moa Sa,Hee Kyoung Choi,Ji Hoon Jeon,Hyeri Seok,Dae Won Park,Su-Hyung Park,Hye Won Jeong,Won Suk Choi,Eui-Cheol Shin +11 more
TL;DR: In this article, SARS-CoV-2-specific CD4+ and CD8+ T cell responses were evaluated in COVID-19 convalescent patients up to 317 days post-symptom onset (DPSO).
Journal ArticleDOI
Rbfox2 dissociation from stress granules suppresses cancer progression.
TL;DR: It is confirmed that Rb fox2, which is present in the nucleus as a splicing regulator, localizes to the cytoplasm of human colon cancer tissues and that induction of Rbfox2 dissociation from SGs by resveratrol treatment inhibits cancer progression, and suggests that R bfox2 could be a potential target for the development of new anticancer drugs.
Journal ArticleDOI
Two-Round Mixed Lymphocyte Reaction for Evaluation of the Functional Activities of Anti-PD-1 and Immunomodulators.
TL;DR: In this two-round MLR, the proliferation of allo-reactive T cells was enhanced by anti-PD-1 in a dose-dependent manner or by immunomodulators, such as lenalidomide and galunisertib, a TGF-β receptor-1 inhibitor.