scispace - formally typeset
H

Heung Kyu Lee

Researcher at KAIST

Publications -  145
Citations -  10629

Heung Kyu Lee is an academic researcher from KAIST. The author has contributed to research in topics: Immune system & Innate immune system. The author has an hindex of 29, co-authored 125 publications receiving 8161 citations. Previous affiliations of Heung Kyu Lee include Yale University & University of Ulsan.

Papers
More filters
Journal ArticleDOI

Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor.

Nikhil S. Joshi, +7 more
- 24 Aug 2007 - 
TL;DR: A mechanism by which the innate immune system sets the relative amounts of a lineage-determining transcription factor in activated CD8(+) T cells and regulates their memory cell potential is elucidated.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Autophagy-Dependent Viral Recognition by Plasmacytoid Dendritic Cells

Heung Kyu Lee, +4 more
- 09 Mar 2007 - 
TL;DR: Results support a key role for autophagy in mediating ssRNA virus detection and interferon-α secretion by pDCs and suggest that cytosolic replication intermediates of viruses serve as pathogen signatures recognized by TLR7.
Journal ArticleDOI

Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus.

Norihiko Watanabe, +6 more
- 25 Aug 2005 - 
TL;DR: It is reported that human Hassall's corpuscles express thymic stromal lymphopoietin (TSLP), indicating a critical role in dendritic-cell-mediated secondary positive selection of medium-to-high affinity self-reactive T cells, leading to the generation of CD4+CD25+ regulatory T cells within the thymus.
Journal ArticleDOI

Distinct Macrophage Phenotypes Contribute to Kidney Injury and Repair

Sik Lee, +10 more
- 01 Feb 2011 - 
TL;DR: Macrophages undergo a switch from a proinflammatory to a trophic phenotype that supports the transition from tubule injury to tubule repair, and this study shows that proinflammatory macrophages worsen kidney damage.