S
Sung Jin Jeong
Researcher at Boston Children's Hospital
Publications - 3
Citations - 402
Sung Jin Jeong is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: GPR56 & Oligodendrocyte. The author has an hindex of 3, co-authored 3 publications receiving 307 citations. Previous affiliations of Sung Jin Jeong include Harvard University.
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Journal ArticleDOI
The Adhesion GPCR GPR126 Has Distinct, Domain-Dependent Functions in Schwann Cell Development Mediated by Interaction with Laminin-211
Sarah C. Petersen,Rong Luo,Ines Liebscher,Stefanie Giera,Sung Jin Jeong,Amit Mogha,Monica Ghidinelli,M. Laura Feltri,Torsten Schöneberg,Xianhua Piao,Kelly R. Monk +10 more
TL;DR: GPR126 has domain-specific functions in SC development whereby the NTF is necessary and sufficient for axon sorting, whereas the CTF promotes wrapping through cAMP elevation, and this work suggests a model in which Laminin-211 mediates GPR126-induced cAMP levels to control early and late stages of SC development.
Journal ArticleDOI
The adhesion G protein-coupled receptor GPR56 is a cell-autonomous regulator of oligodendrocyte development
Stefanie Giera,Yiyu Deng,Rong Luo,Sarah D. Ackerman,Amit Mogha,Kelly R. Monk,Yanqin Ying,Sung Jin Jeong,Manabu Makinodan,Allison R. Bialas,Bernard S. Chang,Beth Stevens,Gabriel Corfas,Xianhua Piao +13 more
TL;DR: It is demonstrated that loss of Gpr56 leads to hypomyelination of the central nervous system in mice, and GPR56 is defined as a cell-autonomous regulator of oligodendrocyte development.
Journal ArticleDOI
Microglial transglutaminase-2 drives myelination and myelin repair via GPR56/ADGRG1 in oligodendrocyte precursor cells
Stefanie Giera,Rong Luo,Yanqin Ying,Yanqin Ying,Sarah D. Ackerman,Sung Jin Jeong,Hannah M. Stoveken,Christopher J. Folts,Christina A. Welsh,Gregory G. Tall,Beth Stevens,Kelly R. Monk,Xianhua Piao +12 more
TL;DR: It is reported that microglia-derived transglutaminase-2 (TG2) signals to ADGRG1 on OL precursor cells (OPCs) in the presence of the ECM protein laminin and that TG2/laminin-dependent activation of AD GRG1 promotes OPC proliferation.