S
Sunil Wadhwa
Researcher at Columbia University
Publications - 44
Citations - 1730
Sunil Wadhwa is an academic researcher from Columbia University. The author has contributed to research in topics: Biglycan & Cartilage. The author has an hindex of 21, co-authored 38 publications receiving 1498 citations. Previous affiliations of Sunil Wadhwa include Columbia University Medical Center & National Institutes of Health.
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Journal ArticleDOI
Extracellular Matrix Proteoglycans Control the Fate of Bone Marrow Stromal Cells
Yanming Bi,Christina H. Stuelten,Tina M. Kilts,Sunil Wadhwa,Renato V. Iozzo,Pamela Gehron Robey,Xiao Dong Chen,Marian F. Young +7 more
TL;DR: Biglycan and decorin appear to be essential for maintaining an appropriate number of mature osteoblasts by modulating the proliferation and survival of bone marrow stromal cells, and underscore the importance of the micro-environment in controlling the fate of adult stem cells.
Journal ArticleDOI
TMJ disorders: future innovations in diagnostics and therapeutics.
Sunil Wadhwa,Sunil Kapila +1 more
TL;DR: Novel findings in biomedicine and developments in imaging and computer technologies are beginning to provide a vision of future innovations in the diagnostics and therapeutics of TMJ disorders, and the identification and use of local or systemic biomarkers to diagnose disease or monitor improvements in therapy.
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Fluid flow induction of cyclo-oxygenase 2 gene expression in osteoblasts is dependent on an extracellular signal-regulated kinase signaling pathway.
Sunil Wadhwa,Stephen L. Godwin,Donald R. Peterson,Mary Anne Farrell Epstein,Lawrence G. Raisz,Carol C. Pilbeam +5 more
TL;DR: FSS transcriptionally induces COX‐2 gene expression in osteoblasts, that the maximum induction requires new protein synthesis, and that induction occurs largely via an ERK signaling pathway.
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Altered functional loading causes differential effects in the subchondral bone and condylar cartilage in the temporomandibular joint from young mice
TL;DR: Altered functional TMJ loading in mice for 2-6 weeks leads to a loss of the condylar cartilage and a transient loss in the density of the mandibular condylars subchondral bone.
Journal ArticleDOI
Fluid flow induces COX-2 expression in MC3T3-E1 osteoblasts via a PKA signaling pathway.
Sunil Wadhwa,Shilpa Choudhary,Maria A. Voznesensky,Mary Anne Farrell Epstein,Lawrence G. Raisz,Carol C. Pilbeam +5 more
TL;DR: In this paper, the authors examined the involvement of the protein kinase A (PKA) and protein Kinase C (PKC) signaling pathways in the peak COX-2 mRNA and luciferase responses to fluid shear stress in MC3T3-E1 osteoblasts.