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Sunil Wadhwa
Researcher at Columbia University
Publications - 44
Citations - 1730
Sunil Wadhwa is an academic researcher from Columbia University. The author has contributed to research in topics: Biglycan & Cartilage. The author has an hindex of 21, co-authored 38 publications receiving 1498 citations. Previous affiliations of Sunil Wadhwa include Columbia University Medical Center & National Institutes of Health.
Papers
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Journal ArticleDOI
Estrogen Promotes Mandibular Condylar Fibrocartilage Chondrogenesis and Inhibits Degeneration via Estrogen Receptor Alpha in Female Mice
Jennifer L. Robinson,Paola Soria,Manshan Xu,Mark Ziggy Vrana,Jeffrey M Luchetti,Helen H. Lu,Jing Chen,Sunil Wadhwa +7 more
TL;DR: A mechanistic understanding of estradiol on TMJ growth and homeostasis is provided and can be utilized for development of therapeutic targets to promote regeneration and inhibit degeneration of the mandibular condylar fibrocartilage.
Journal Article
Small leucine-rich proteoglycans in the aging skeleton.
Marian F. Young,Yanming Bi,Laurent Ameye,T. Xu,Sunil Wadhwa,Anne-Marie Heegaard,Tina M. Kilts,Xiao Dong Chen +7 more
TL;DR: This review outlines the novel research findings uncovered using these new animal models to examine SLRP function, and examines them at the tissue, cell and molecular levels.
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Impaired posterior frontal sutural fusion in the biglycan/decorin double deficient mice
Sunil Wadhwa,Yanming Bi,Ana T. Ortiz,Mildred C. Embree,Tina M. Kilts,Renato V. Iozzo,Lynne A. Opperman,Marian F. Young +7 more
TL;DR: Failure of PFS fusion and hypomineralization of the calvaria in the Bgn/Dcn double deficient mice demonstrates that these extracellular matrix proteoglycans could have a role in controlling the formation and growth of the cranial vault.
Journal ArticleDOI
Orthodontic tooth movement causes decreased promoter expression of collagen type 1, bone sialoprotein and alpha-smooth muscle actin in the periodontal ligament.
TL;DR: An in vivo tooth movement model using transgenic mice containing transgenes of these promoters fused to green fluorescent proteins (GFP) provides an efficient and effective way of investigating the cellular events underlying orthodontic tooth movement.
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Sex Differences in Chondrocyte Maturation in the Mandibular Condyle from a Decreased Occlusal Loading Model
J. Chen,Takanori Sobue,Achint Utreja,Zana Kalajzic,M. Xu,Tina M. Kilts,M. F. Young,Sunil Wadhwa +7 more
TL;DR: Investigation of sex differences in CD-1 and C57BL/6 mice exposed to a decreased occlusal loading TMJ remodeling model found decreased bone volume in both sexes and a decrease in early chondrocyte maturation exclusively in female mice.